Evaluation of efficacy of experimental gel to foam dentifrices in dental erosion

•General and Oral Health: Good general health with (in the opinion of the investigator) no clinically OST and OHT examinations. •Oral Requirements: –An intact maxillary dental arch suitable for the retention of the palatal appliance and an intact mandibular dental arch. Subjects may have fixed bridges replacing missing teeth. –A gum base stimulated whole saliva flow rate ≥ 0.8 g/min and an unstimulated whole saliva flow rate ≥ 0.2 g/min. •Contraception: Women of childbearing potential who are, in the opinion of the investigator, practicing a reliable method of contraception.

•Oral Health: – Current active caries or periodontal disease that may compromise the study or the health of the subjects. – Lesions of the oral cavity that could interfere with the study evaluations, including severe gingivitis, grossly carious lesions, periodontitis and other severe periodontal disease. •Allergy/Intolerance: Known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients. •Clinical Study/Experimental Medication: –Participation in another clinical study or receipt of an investigational drug within 30 days of the screening visit –Previous participation in this study •Substance abuse: Recent history (within the last year) of alcohol or other substance abuse. •Pregnancy: Women who are pregnant or who are intending to become pregnant over the duration of the study •Breast-feeding: Women who are breast–feeding