Last updated: 11/07/2018 18:29:49
A randomised, double-blind, placebo-controlled multicentre parallel-group study to compare the efficacy and safety of a single intravenous bolus dose of ondansetron, metoclopramide and placebo in the prevention of postoperative nausea and emesis in patients having general anaesthesia and undergo ...
Clinicaltrials.gov ID
Not applicable
EudraCT ID
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EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A randomised, double-blind, placebo-controlled multicentre parallel-group study to compare the efficacy and safety of a single intravenous bolus dose of ondansetron, metoclopramide and placebo in the prevention of postoperative nausea and emesis in patients having general anaesthesia and undergo ...
Trial description: A randomised, double-blind, placebo-controlled multicentre parallel-group study to compare the efficacy and safety of a single intravenous bolus dose of ondansetron, metoclopramide and placebo in the prevention of postoperative nausea and emesis in patients having general anaesthesia and undergo ...
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. Chen, P. P., Chui, P. T., and Gin, T. Eur J Anaesthesiol 96; 13 (5):485-91
International, multicentre, placebo-controlled study to evaluate the effectiveness of ondansetron vs. metoclopramide in the prevention of post-operative nausea and vomiting. Morris, R. W., Aune, H., Feiss, P., Hanson, A., Hasselstrom, L., Maltby, J. R., Rocke, D. A., Rozenberg, B., Rust, M., and Cohen, L. A. Eur J Anaesthesiol 98; 15.(1):69-79
[Intravenous administration of ondansetron vs. metoclopramide for the prophylaxis of postoperative nausea and vomiting] Rust, M. Anaesthesist 95; 44.(4):288-90.
Medical condition
Nausea and Vomiting, Postoperative
Product
ondansetron
Collaborators
Not applicable
Study date(s)
September 1992 to May 1993
Type
Not applicable
Phase
3
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1993-31-05
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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