Last updated: 11/07/2018 18:29:09
A randomised, double-blind, parallel group study to compare the efficacy and safety of ondansetron (GR38032F) plus dexamethasone with metoclopramide plus dexamethasone in the prophylaxis of nausea and emesis induced by carboplatin chemotherapy.
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A randomised, double-blind, parallel group study to compare the efficacy and safety of ondansetron (GR38032F) plus dexamethasone with metoclopramide plus dexamethasone in the prophylaxis of nausea and emesis induced by carboplatin chemotherapy.
Trial description: A randomised, double-blind, parallel group study to compare the efficacy and safety of ondansetron (GR38032F) plus dexamethasone with metoclopramide plus dexamethasone in the prophylaxis of nausea and emesis induced by carboplatin chemotherapy.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
A randomised, double-blind, parallel-group study to compare the efficacy and safety of ondansetron (gr38032f) plus dexamethasone with metoclopramide plus dexamethasone in the prophylaxis of nausea and emesis induced by carboplatin chemotherapy. du Bois, A., McKenna, C. J., Andersson, H., Lahousen, M., Kitchener, H., Pinter, T., Capstick, V., and Wilkinson, J. R. Oncology 97; 54 (1):7-14
Efficacy of Ondansetron and Metoclopramide (With Dexamethasone): In The Prevention of Carboplatin-Induced Emesis, Du Bois, A; Andersson, H; Lahousen, M; Kitchener, H; Pinter, T; Capstick, V; McKenna, C J. ECCO 8: 8th European Conference on Clinical Oncology and Cancer Nursing. 10/29/1995 Paris; France.
Medical condition
Nausea and Vomiting, Chemotherapy-Induced
Product
ondansetron
Collaborators
Not applicable
Study date(s)
August 1993 to July 1994
Type
Not applicable
Phase
4
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1994-28-07
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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