Last updated: 11/04/2018 10:27:38
Meta-analysis of ranitidine in meal-induced heartburn
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Finalized
Finalized
Trial overview
Official title: Meta-analysis of the efficacy of ranitidine 75mg and ranitidine 150mg versus placebo on the reduction of severity or prevention of meal-induced heartburn
Trial description: This is a meta-analysis of ranitidine data evaluating the use of ranitidine in the prevention or reduction in severity of meal-induced heartburn. From the GSK database 6 studies have been identified which investigated doses of 75mg and 150mg ranitidine when taken prior to a heartburn inducing meal. All of the 6 studies have similar designs apart from variations in dose and the time between dose.
Primary purpose:
Treatment
Trial design:
Parallel Assignment
Masking:
Double (Participant, Investigator)
Allocation:
Randomized
Primary outcomes:
Heartburn severity measured by AUC
Timeframe: Up to 5 hours post dose
Secondary outcomes:
Not applicable
Interventions:
Drug: 75mg ranitidine
Drug: 150mg ranitidine
Drug: Placebo
Enrollment:
3341
Observational study model:
Not applicable
Primary completion date:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Not applicable
Medical condition
Heartburn
Product
ranitidine
Collaborators
Not applicable
Study date(s)
March 2010 to April 2010
Type
Observational
Phase
Not applicable
Participation criteria
Sex
Female & Male
Age
18+ years
Accepts healthy volunteers
none
- Not applicable for this meta-analysis.
Inclusion and exclusion criteria
Inclusion criteria:
- Not applicable for this meta-analysis.
Trial location(s)
No location data available.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Refer to study documents
Recruitment status
Finalized
Actual primary completion date
Not applicable
Actual study completion date
2010-11-04
Plain language summaries
Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.
Additional information about the trial
Not applicable
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