Last updated: 11/07/2018 17:33:54
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of MALARONE (Atovaquone and Proguanil Hydrochloride) for the Prevention of Plasmodium falciparum Malaria in Gabonese Children, and the Effect on Antibody Response to Typhoid and Cholera Vacci ...
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of MALARONE (Atovaquone and Proguanil Hydrochloride) for the Prevention of Plasmodium falciparum Malaria in Gabonese Children, and the Effect on Antibody Response to Typhoid and Cholera Vacci ...
Trial description: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of MALARONE (Atovaquone and Proguanil Hydrochloride) for the Prevention of Plasmodium falciparum Malaria in Gabonese Children, and the Effect on Antibody Response to Typhoid and Cholera Vacci ...
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Abstract: Plasmodium falciparum prophylaxis with atovaquone and proguanil when administered in combination with typhoid and cholera vaccines in gabonese children. Faucher, J F, Borrmann, S, Binder, R K, Missinou, M A, Gruss, H, Neubauer, R, Matsiegui, P B, Que, J U, Miller, G B, Lell, B, and Kremsner, P G American Society of Tropical Medicine and Hygiene 50th Annual Meeting 11/11/2001 Atlanta, GA; USA
Faucher, J. F., Binder, R., Missinou, M. A., Matsiegui, P. B., Gruss, H., Neubauer, R., Lell, B., Que, J. U., Miller, G. B., and Kremsner, P. G. Efficacy of atovaquone/proguanil for malaria prophylaxis in children and its effect on the immunogenicity of live oral typhoid and cholera vaccines. Clinical Infectious Diseases; 35(10):1147-1154, 2002
Medical condition
Malaria, Falciparum
Product
atovaquone/proguanil
Collaborators
Not applicable
Study date(s)
February 2000 to July 2000
Type
Not applicable
Phase
4
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
2000-15-07
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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