Last updated: 11/07/2018 16:54:30
A double-blind, double-dummy, randomized, parallel group comparison of the efficacy and safety of fluticasone propionate aqueous nasal spray 200mcg QD versus astemizole 10mg QD versus placebo for two weeks in patients with seasonal allergic rhinitis
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A double-blind, double-dummy, randomized, parallel group comparison of the efficacy and safety of fluticasone propionate aqueous nasal spray 200mcg QD versus astemizole 10mg QD versus placebo for two weeks in patients with seasonal allergic rhinitis
Trial description: A double-blind, double-dummy, randomized, parallel group comparison of the efficacy and safety of fluticasone propionate aqueous nasal spray 200mcg QD versus astemizole 10mg QD versus placebo for two weeks in patients with seasonal allergic rhinitis
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Alvarado C, Reed T, Gleich E, et al. Fluticasone propionate aqueous nasal spray reduces eosinophils and cytokine activity of patients with allergic rhinitis. J Allergy Clin Immunol 1995;95:193 (abstract);
Alvarado-Valdés CA, Blomgren J, Weiler D, Gleich GJ, Reed CE, Field EA, Wisniewski ME, Pobiner BF. The effect of fluticasone propionate aqueous nasal spray on eosinophils and cytokines in nasal secretions of patients with ragweed allergic rhinitis. Clinical Therapeutics 1997;Vol. 19, No. 2:273-281
Stricker WE, Klimas JT, Mendelson L, et al. Intranasal fluticasone propionate is more effective than astemizole for seasonal allergic rhinitis. Ann Allergy 1994;72(1):86 (abstract)
Medical condition
Rhinitis, Allergic, Seasonal
Product
fluticasone propionate
Collaborators
Not applicable
Study date(s)
July 1991 to November 1991
Type
Not applicable
Phase
4
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1991-06-11
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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