Last updated: 11/04/2018 06:12:18
Study Of Denagliptin In Subjects With Type 2 Diabetes Mellitus (T2DM)
GSK study ID
DPB107246
Clinicaltrials.gov ID
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Other
Other
Trial overview
Official title: A multi-center, double-blind, parallel-group, randomized, placebo-controlled study to evaluate the efficacy, safety, and tolerability of denagliptin in subjects with type 2 diabetes mellitus
Trial description: GW823093 is a selective DPP-IV Inhibitor and is being investigated as a once a day oral therapy. The purpose of the Study is to evaluate the effectiveness, safety, and tolerability of 2 doses of GW823093, compared to placebo, taken once daily in patients with Type 2 diabetes mellitus.
Primary purpose:
Treatment
Trial design:
Parallel Assignment
Masking:
Not applicable
Allocation:
Randomized
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Enrollment:
0
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Not applicable
Medical condition
Type 2 Diabetes Mellitus
Product
denagliptin
Collaborators
Not applicable
Study date(s)
October 2006 to October 2007
Type
Interventional
Phase
2/3
Participation criteria
Sex
Female & Male
Age
18 - 75 Years
Accepts healthy volunteers
no
- Type 2 diabetes mellitus treated with diet and exercise or oral anti-diabetic treatment
- Body mass index between 20 and 40
- Subjects with previous use of insulin
- Type 1 diabetes
Inclusion and exclusion criteria
Inclusion criteria:
- Type 2 diabetes mellitus treated with diet and exercise or oral anti-diabetic treatment
- Body mass index between 20 and 40
- Females of childbearing potential must use adequate birth control.
Exclusion criteria:
- Subjects with previous use of insulin
- Type 1 diabetes
- Uncontrolled thyroid disease
- History of drug or alcohol abuse in the past year
- Any other clinically significant disease.
Trial location(s)
Location
GSK Clinical Trials Call Center
Calhoun, GA, United States, 30701
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Hollywood, FL, United States, 33023
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Charlotte, NC, United States, 28277
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Lake Zurich, IL, United States, 60047
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Hialeah, FL, United States, 33010
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Baton Rouge, LA, United States, 70809
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Tucson, AZ, United States, 85710
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Coral Gables, FL, United States, 33134
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Florissant, MO, United States, 63031
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Roswell, GA, United States, 30076
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Warminster, PA, United States, 18974
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Marrero, LA, United States, 70072
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Oxon Hill, MD, United States, 20745
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Cincinnati, OH, United States, 45219
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Victorville, CA, United States, 92392
Status
Study Stopped
Location
GSK Clinical Trials Call Center
St. Louis, MO, United States, 63128
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Guthrie, OK, United States, 73044
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Torrance, CA, United States, 90505
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Las Vegas, NV, United States, 89128
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Medford, OR, United States, 97504
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Concord, CA, United States, 94520-2054
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Wilmington, DE, United States, 19805
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Williamsville, NY, United States, 14221
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Cleburne, TX, United States, 76033
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Beverly Hills, CA, United States, 90211
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Anderson, SC, United States, 29621
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Columbus, OH, United States, 43207
Status
Study Stopped
Location
GSK Clinical Trials Call Center
St. Peters, MO, United States, 63376
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Tallassee, AL, United States, 36078
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Phoenix, AZ, United States, 85016
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Norman, OK, United States, 73069
Status
Study Stopped
Location
GSK Clinical Trials Call Center
San Antonio, TX, United States, 78205
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Opalocka, FL, United States, 33054
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Johnson City, TN, United States, 37601
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Fleetwood, PA, United States, 19522
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Chicago, IL, United States, 60610
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Carmichael, CA, United States, 95608
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Plantation, FL, United States, 33324
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Morehead City, NC, United States, 28557
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Melbourne, FL, United States, 32901
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Chattanooga, TN, United States, 37404
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Eugene, OR, United States, 97404
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Hayden Lake, ID, United States, 83835-2108
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Detroit, MI, United States, 48235
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Beaver Falls, PA, United States, 15010
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Weber City, VA, United States, 24290
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Seguin, TX, United States, 78155
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Oklahoma City, OK, United States, 73112-5550
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Chicago, IL, United States, 60616
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Boynton Beach, FL, United States, 33435
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Watseka, IL, United States, 60970
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Oklahoma City, OK, United States, 73116
Status
Study Stopped
Location
GSK Clinical Trials Call Center
Clearwater, FL, United States, 33765
Status
Study Stopped
Study documents
No study documents available.
Results overview
Study Results yet to be posted
Recruitment status
Other
Actual primary completion date
Not applicable
Actual study completion date
Not applicable
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Additional information
Not applicable
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