Last updated: 11/07/2018 14:40:35
A Study to Assess the Effects of BRL 49653C on the Pharmacokinetics of Digoxin in Healthy Adult Males
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A Study to Assess the Effects of BRL 49653C on the Pharmacokinetics of Digoxin in Healthy Adult Males
Trial description: A Study to Assess the Effects of BRL 49653C on the Pharmacokinetics of Digoxin in Healthy Adult Males
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Abstract: Chronic Administration Of Rosiglitazone (RSG) Does Not Alter The Pharmacokinetics Of Digoxin, Jorkasky, Diane K, MD; Freed, Martin I, MD; DiCicco, Robert A, MD; Allen, Ann, MD. SmithKline Beecham Pharmaceuticals, Philadelphia, PA; Chicago, IL; USA. American Diabetes Association 58th Annual Meeting and Scientific Sessions. 6/13/1998
DiCicco RA, Allen A, Jorkasky DK, Freed MI. Chronic administration of rosiglitazone does not alter the pharmacokinetics of digoxin. Diabetes 1998; 47 (Suppl 1): A353. Presented at ADA 1998.
DiCicco RA, Miller AK, Patterson S, Freed MI. Rosiglitazone does not affect the steady-state pharmacokinetics of digoxin. J Clin Pharmacol 2000; 40: 1516-1521.
Drug interactions of clinical importance with antihyperglycaemic agents: an update. Scheen, A. J. Drug Saf 2005; 28(7):601-31
Rosiglitazone does not affect the steady-state pharmacokinetics of digoxin. Di Cicco, R. A., Miller, A. K., Patterson, S., and Freed, M. I. J Clin Pharmacol 2000; 40(12 Pt 2):1516-21
Rosiglitazone. Balfour, J. A. and Plosker, G. L. Drugs 99; 57(6):921-30; discussion 931-2
Medical condition
Diabetes Mellitus
Product
rosiglitazone
Collaborators
Not applicable
Study date(s)
July 1996 to September 1996
Type
Not applicable
Phase
1
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1996-19-09
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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