Last updated: 11/07/2018 13:57:18
To assess the effect of repeated dosing with paroxetine, amitriptyline and placebo on psychomotor skills and cardiac function in volunteers
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: To assess the effect of repeated dosing with paroxetine, amitriptyline and placebo on psychomotor skills and cardiac function in volunteers
Trial description: To assess the effect of repeated dosing with paroxetine, amitriptyline and placebo on psychomotor skills and cardiac function in volunteers
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Cardiovascular and psychomotor effects of repeated doses of paroxetine: a comparison with amitriptyline and placebo in healthy men. Warrington, S. J., Dana-Haeri, J., and Sinclair, A. J. Acta Psychiatr Scand Suppl 89; 350(42-4)
Cardiovascular effects of antidepressants: studies of paroxetine in healthy men and depressed patients. Warrington, S. J. and Lewis, Y. Int Clin Psychopharmacol 92; 6 Suppl 4(59-64)
Medical condition
Depressive Disorder
Product
paroxetine
Collaborators
Not applicable
Study date(s)
N/A to Invalid Date
Type
Not applicable
Phase
1
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
Not applicable
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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