Safety and effectiveness of Belantamab Mafodotin for Multiple Myeloma using the Flatiron Health Database
Trial overview
Number of participants with clinical care, demographics characteristics, disease and treatment history
Timeframe: At index date
Number of participants with ocular adverse event of special interests (AESIs) related to belantamab mafodotin Treatment (overall and subgroup)
Timeframe: At post-index treatment period
Number of ophthalmic monitoring visits relative to belantamab mafodotin administration
Timeframe: At index date and post-index treatment period
Time of ophthalmic monitoring visits relative to belantamab mafodotin administration
Timeframe: At index date and post-index treatment period
Number of participants with ocular AESIs (overall and subgroup)
Timeframe: At post-index period
Number of participants with impact on treatment discontinuation, delay, and dose modification due to ocular AESIs (overall and subgroup)
Timeframe: At post-index period
Number of participants persistent and adherent to belantamab mafodotin
Timeframe: At post-index period
Number of participants with reasons for treatment discontinuation
Timeframe: At post-index period
Number of participants with reasons for treatment delays, or dose modifications
Timeframe: At post-index period
Overall response rate (ORR)
Timeframe: At post-index period
Duration of response (DoR)
Timeframe: At post-index period
Duration of treatment (DoT)
Timeframe: At post-index period
Time to next treatment (TTNT)
Timeframe: At post-index period
Real-world progression free survival (rwPFS)
Timeframe: At post-index period
Overall survival (OS)
Timeframe: At post-index period
- Confirmed diagnosis of Multiple myeloma (MM)
- Greater than or equal to (>=) 1 record for belantamab mafodotin (first observed record defines the index date)
- Participation in an interventional clinical trial during the Baseline period or on the index date ( that is [i.e.,] time of the first belantamab mafodotin administration)
- Identification of participation in an interventional clinical trial will be based on records for administration of clinical study drugs, contingent on data availability
- Confirmed diagnosis of Multiple myeloma (MM)
- Greater than or equal to (>=) 1 record for belantamab mafodotin (first observed record defines the index date)
- Greater than or equal to (>=) 18 years at index date
- Participation in an interventional clinical trial during the Baseline period or on the index date ( that is [i.e.,] time of the first belantamab mafodotin administration)
- Identification of participation in an interventional clinical trial will be based on records for administration of clinical study drugs, contingent on data availability
- If a participant participated in an interventional clinical trial after belantamab mafodotin administration, the date of the first record for participation in the interventional clinical trial would represent the end of the participant’s study period
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
If you wish to request for full study report, please contact - [email protected]
Results overview
Refer to study documents
Plain language summaries
Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.