Last updated: 02/08/2019 18:50:19

Discrete Choice Experiment in Severe Asthma

GSK study ID
205816
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Cancelled
Cancelled
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Discrete Choice Experiment in Severe Asthma
Trial description: With increasing treatment options such as Mepolizumab and Omalizumab for severe asthma, there is an increasing need for identification and assessment of subject preferences to improve medication adherence. Therefore the aim of this study is to determine severe asthma subject preference for various treatment attributes like mode of administration, frequency of dosing, willingness to pay, effectiveness, safety using Discrete Choice Experiment (DCE) methodology. DCE is a type of preference study which asks subjects to make a choice between different attributes of importance in the form of a questionnaire. There are 3 stages in design of DCE and after completing all 3 stages, subject preference attributes to be studied will be selected and the DCE subject questionnaire will be developed. In the survey, subjects will be presented with discrete choice between scenarios and will be asked which one they would choose. It is expected that between 30 and 40 subjects with severe persistent asthma will participate in the final online survey from each country (N= ~150-200).
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

Identification of severe asthma subject preference

Timeframe: Single time point

Estimation of the relative importance of each attribute

Timeframe: Single time point

Evaluation of a preference weight for each level of the attribute

Timeframe: Single time point

Evaluation of willingness to pay by subjects

Timeframe: single time point

Secondary outcomes:
Not applicable
Interventions:
Other: DCE questionnaire
Enrollment:
0
Observational study model:
Cohort
Primary completion date:
2018-04-05
Time perspective:
Cross-Sectional
Clinical publications:
Not applicable
Medical condition
Asthma
Product
mepolizumab
Collaborators
Not applicable
Study date(s)
December 2016 to May 2018
Type
Observational
Phase
Not applicable

Participation criteria

Sex
Female & Male
Age
18+ years
Accepts healthy volunteers
Not applicable
  • Inclusion Criteria:
  • Subject with severe persistent asthma will be included in this analysis.

Trial location(s)

No location data available.

Study documents

No study documents available.

Results overview

No study documents available

Recruitment status
Cancelled
Actual primary completion date
Not applicable
Actual study completion date
Not applicable

Plain language summaries

Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

Additional information about the trial

Not applicable
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