Last updated: 02/08/2019 18:50:19

Discrete Choice Experiment in Severe Asthma

GSK study ID
205816
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Other
Other
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Discrete Choice Experiment in Severe Asthma
Trial description: With increasing treatment options such as Mepolizumab and Omalizumab for severe asthma, there is an increasing need for identification and assessment of subject preferences to improve medication adherence. Therefore the aim of this study is to determine severe asthma subject preference for various treatment attributes like mode of administration, frequency of dosing, willingness to pay, effectiveness, safety using Discrete Choice Experiment (DCE) methodology. DCE is a type of preference study which asks subjects to make a choice between different attributes of importance in the form of a questionnaire. There are 3 stages in design of DCE and after completing all 3 stages, subject preference attributes to be studied will be selected and the DCE subject questionnaire will be developed. In the survey, subjects will be presented with discrete choice between scenarios and will be asked which one they would choose. It is expected that between 30 and 40 subjects with severe persistent asthma will participate in the final online survey from each country (N= ~150-200).
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

Identification of severe asthma subject preference

Timeframe: Single time point

Estimation of the relative importance of each attribute

Timeframe: Single time point

Evaluation of a preference weight for each level of the attribute

Timeframe: Single time point

Evaluation of willingness to pay by subjects

Timeframe: single time point

Secondary outcomes:
Not applicable
Interventions:
  • Other: DCE questionnaire
  • Enrollment:
    0
    Primary completion date:
    2018-04-05
    Observational study model:
    Cohort
    Time perspective:
    Cross-Sectional
    Clinical publications:
    Not applicable
    Medical condition
    Asthma
    Product
    mepolizumab
    Collaborators
    Not applicable
    Study date(s)
    December 2016 to May 2018
    Type
    Observational
    Phase
    Not applicable

    Participation criteria

    Sex
    Female & Male
    Age
    18+ years
    Accepts healthy volunteers
    Not applicable
    • Inclusion Criteria:
    • Subject with severe persistent asthma will be included in this analysis.

    Trial location(s)

    This study does not involve prospective enrollment of participants.

    Study documents

    No study documents available.

    Results overview

    No study documents available

    Recruitment status
    Other
    Actual primary completion date
    Not applicable
    Actual study completion date
    Not applicable

    Plain language summaries

    Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

    Additional information about the trial

    Not applicable
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