Last updated: 11/03/2018 22:46:03
Heat, eat, compete: Investigating the application of localised heating on muscle glycogen
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Completed
Completed
Trial overview
Official title: Heat, eat, compete: Investigating the application of localised heating on muscle glycogen
Trial description: Muscle glycogen is a rate limiter to endurance performance. It is common practice for endurance athletes to undertake a form of carbohydrate loading prior to a major event to enhance pre exercise muscle glycogen levels. Some new research has demonstrated that localised heating of a muscle group post exercise can enhance the rate to carbohydrate repletion. This has not been investigated in a rested state pre exercise. Thus the study is designed to investigate the impact localised heating has on muscle glycogen synthesis at rest. The participant will undertake a 24 hour period of carbohydrate loading prior to visiting the lab. During the trial the participant will have one leg heated, with the other leg exposed to ambient conditions. A bilateral muscle biopsy will be collected pre and post heating to quantify muscle glycogen.
Primary purpose:
Other
Trial design:
Parallel Assignment
Masking:
None (Open Label)
Allocation:
Randomized
Primary outcomes:
Muscle glycogen content.
Timeframe: Baseline to 120 min
Secondary outcomes:
Validity (correlation and agreement) between the biopsy and ultra sound muscle glycogen quantification methods.
Timeframe: Baseline to 120 minutes
Interventions:
Other: Room temperature
Procedure: Heated Trousers
Enrollment:
16
Observational study model:
Not applicable
Primary completion date:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Not applicable
Medical condition
Sports Nutritional Sciences
Product
lidocaine
Collaborators
Not applicable
Study date(s)
June 2015 to October 2015
Type
Interventional
Phase
Not applicable
Participation criteria
Sex
Female & Male
Age
18 - 35 Year
Accepts healthy volunteers
yes
- Capable of understanding, willing to provide signed and dated copy of informed consent form.
- Males and females between ages of 18-35 years.
- Female who is pregnant, intending to become pregnant, or breast feeding.
- Use of concomitant medication known to be over the counter (OTC) analgesics (24 hours prior to first assessment visit).
Inclusion and exclusion criteria
Inclusion criteria:
- Capable of understanding, willing to provide signed and dated copy of informed consent form. -Males and females between ages of 18-35 years. -BMI should be between 18.0-24.9 (kg/m2) inclusive. -Good in general and mental health with no clinically significant and relevant abnormalities in medical history in the opinion of the investigator or medically qualified designee. -Must be physically active and exercise at a moderate/high intensity greater than (>) 3 times per week for > 30 minutes (min) at a time with no chronic illness and currently free from acute illness. -Ability and willingness to follow all study procedures and successfully complete the study.
Exclusion criteria:
- Female who is pregnant, intending to become pregnant, or breast feeding. -Use of concomitant medication known to be over the counter (OTC) analgesics (24 hours prior to first assessment visit). -Known or suspected intolerance or hypersensitivity to the study materials or any of -their stated ingredients. -Has a history of or current evidence (within last 5 years) of abuse of alcohol or other substance. -Vegetarian/vegan or follows any other diet regime excludes certain food groups. -Consuming nutritional supplements in the 48 hours pre trial.
Trial location(s)
No location data available.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Refer to study documents
Recruitment status
Completed
Actual primary completion date
Not applicable
Actual study completion date
2015-28-10
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Additional information
Not applicable
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