Last updated: 02/04/2020 14:50:10

Reasons for discontinuation of injectable diabetes medications: wave 2

GSK study ID
201114
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Reasons for discontinuation of injectable diabetes medications: wave 2
Trial description: Patients with type 2 diabetes mellitus (T2DM) who are treated with currently marketed glucagon-like peptide-1 (GLP-1) agonists had a higher rate of non-persistence (discontinuation) than patients on other anti-diabetic agents. This study is exploratory in nature with a primary goal of describing which characteristics are most commonly associated with discontinuing injectable T2DM therapy. The primary objective of this study is to identify the self-reported reasons for non-persistence among subjects initiating an injectable diabetes medication and to describe the decision-making process for discontinuation. The secondary objectives include describing perceived value of patient support programs and identifying differences between continuers and discontinuers in terms of perceived or experienced barriers to taking the medications. Subjects for this study will be recruited from Harris Interactive’s Chronic Illness Panel (CIP) and/or other third‐party online panels. The study design is a cross-sectional, internet-based survey.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

Reasons for discontinuation

Timeframe: 1 year

Secondary outcomes:

Subject characteristics

Timeframe: 1 year

Interventions:
  • Drug: exenatide QW
  • Drug: insulin
  • Drug: liraglutide
  • Enrollment:
    0
    Primary completion date:
    2014-13-06
    Observational study model:
    Cohort
    Time perspective:
    Prospective
    Clinical publications:
    Spain CV, Wright JJ, Hahn RM, Wivel A, Martin AA. Self-reported barriers to adherence and persistence to treatment with injectable medications for Type 2 diabetes. Clin Ther. 2016;38(7):1653-1669.
    Medical condition
    Diabetes Mellitus, Type 2
    Product
    albiglutide, insulin human, liraglutide
    Collaborators
    Not applicable
    Study date(s)
    October 2013 to June 2014
    Type
    Observational
    Phase
    Not applicable

    Participation criteria

    Sex
    Female & Male
    Age
    18+ years
    Accepts healthy volunteers
    none
    • Age 18 or older
    • A diagnosis of Type 2 diabetes
    • Younger than age 18

    Trial location(s)

    This study does not involve prospective enrollment of participants.

    Study documents

    Clinical study report
    Available language(s): English
    Scientific result summary
    Available language(s): English
    Protocol
    Available language(s): English

    If you wish to request for full study report, please contact - [email protected]

    Results overview

    Refer to study documents

    Recruitment status
    Study complete
    Actual primary completion date
    2014-13-06
    Actual study completion date
    2014-13-06

    Plain language summaries

    Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

    Additional information about the trial

    Not applicable
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