Last updated: 02/04/2020 14:50:10

Reasons for discontinuation of injectable diabetes medications: wave 2

GSK study ID
201114
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Finalized
Finalized
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Reasons for discontinuation of injectable diabetes medications: wave 2
Trial description: Patients with type 2 diabetes mellitus (T2DM) who are treated with currently marketed glucagon-like peptide-1 (GLP-1) agonists had a higher rate of non-persistence (discontinuation) than patients on other anti-diabetic agents. This study is exploratory in nature with a primary goal of describing which characteristics are most commonly associated with discontinuing injectable T2DM therapy. The primary objective of this study is to identify the self-reported reasons for non-persistence among subjects initiating an injectable diabetes medication and to describe the decision-making process for discontinuation. The secondary objectives include describing perceived value of patient support programs and identifying differences between continuers and discontinuers in terms of perceived or experienced barriers to taking the medications. Subjects for this study will be recruited from Harris Interactive’s Chronic Illness Panel (CIP) and/or other third‐party online panels. The study design is a cross-sectional, internet-based survey.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

Reasons for discontinuation

Timeframe: 1 year

Secondary outcomes:

Subject characteristics

Timeframe: 1 year

Interventions:
Drug: exenatide QW
Drug: insulin
Drug: liraglutide
Enrollment:
0
Observational study model:
Cohort
Primary completion date:
2014-13-06
Time perspective:
Prospective
Clinical publications:
Spain CV, Wright JJ, Hahn RM, Wivel A, Martin AA. Self-reported barriers to adherence and persistence to treatment with injectable medications for Type 2 diabetes. Clin Ther. 2016;38(7):1653-1669.
Medical condition
Diabetes Mellitus, Type 2
Product
albiglutide, insulin human, liraglutide
Collaborators
Not applicable
Study date(s)
October 2013 to June 2014
Type
Observational
Phase
Not applicable

Participation criteria

Sex
Female & Male
Age
18+ years
Accepts healthy volunteers
none
  • Age 18 or older
  • A diagnosis of Type 2 diabetes
  • Younger than age 18

Trial location(s)

No location data available.

Study documents

Clinical study report
Available language(s): English
Scientific result summary
Available language(s): English
Protocol
Available language(s): English

If you wish to request for full study report, please contact - [email protected]

Results overview

Refer to study documents

Recruitment status
Finalized
Actual primary completion date
2014-13-06
Actual study completion date
2014-13-06

Plain language summaries

Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

Additional information about the trial

Not applicable
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