Last updated: 03/05/2020 20:30:14
This product has been transferred to Novartis. GSK Clinical Study Register is no longer maintained for this study.

Meta-Analysis of Systemic Treatment for Advanced Renal Cell Carcinoma: is Proression-Free Survival a Surrogate for Overall Survival?

GSK study ID
115281
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
No longer a GSK study
No longer a GSK study
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Meta-Analysis of Systemic Treatment for Advanced Renal Cell Carcinoma: is Proression-Free Survival a Surrogate for Overall Survival?
Trial description: Individual patient data meta-analysis to assess what extent surrogate endpoints, such as ORR and PFS, correlate with and may be used as surrogates for OS.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

PFS

Timeframe: 5294

Secondary outcomes:

Tumor Response

Timeframe: 5294

Cytokines

Timeframe: 5294

OS

Timeframe: 5294

Interventions:
Not applicable
Enrollment:
1
Primary completion date:
Not applicable
Observational study model:
Case-Only
Time perspective:
Retrospective
Clinical publications:
Not applicable
Medical condition
Carcinoma, Renal Cell
Product
pazopanib
Collaborators
Not applicable
Study date(s)
December 2010 to Invalid Date
Type
Observational
Phase
Not applicable

Participation criteria

Sex
Not applicable
Age
18+ years
Accepts healthy volunteers
none
  • Randomized clinical trial patient data from Ph II or Ph III trials
  • Patient accrual initiated in or after 1/1992
Inclusion and exclusion criteria
Inclusion criteria:
  • Randomized clinical trial patient data from Ph II or Ph III trials
  • Patient accrual initiated in or after 1/1992
  • Closed to patient accrual in or before 12/2010

Trial location(s)

This study does not involve prospective enrollment of participants.

Study documents

No study documents available.

Results overview

No study documents available

Recruitment status
No longer a GSK study
Actual primary completion date
Not applicable
Actual study completion date
Not applicable

Plain language summaries

Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

Additional information about the trial

Not applicable
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