Last updated: 11/07/2018 08:29:05
An Open Study to Determine Whether 566C80 (Atovaquone) Exhibits Antimalarial Activity in Thai Patients with P. falciparum Malaria
Clinicaltrials.gov ID
Not applicable
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: An Open Study to Determine Whether 566C80 (Atovaquone) Exhibits Antimalarial Activity in Thai Patients with P. falciparum Malaria
Trial description: An Open Study to Determine Whether 566C80 (Atovaquone) Exhibits Antimalarial Activity in Thai Patients with P. falciparum Malaria
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Looareesuwan S. Viravan C. Webster HK. Kyle DE. Hutchinson DB. Canfield CJ. Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. American Journal of Tropical Medicine & Hygiene. 54:62-6, 1996.
Pharmacokinetics of proguanil in malaria patients treated with proguanil plus atovaquone. Edstein, M. D., Looareesuwan, S., Viravan, C., and Kyle, D. E. Southeast Asian J Trop Med Public Health 96; 27(2):216-20
Proguanil polymorphism does not affect the antimalarial activity of proguanil combined with atovaquone in vitro. Edstein, M. D., Yeo, A. E., Kyle, D. E., Looareesuwan, S., Wilairatana, P., and Rieckmann, K. H. Trans R Soc Trop Med Hyg 96; 90(4):418-21
Medical condition
Malaria
Product
atovaquone/proguanil
Collaborators
Not applicable
Study date(s)
October 1990 to July 1993
Type
Not applicable
Phase
2
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1993-15-07
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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