Last updated: 11/03/2018 15:17:24
European Cost of Asthma TreatmentEU-COAST
GSK study ID
113553
Clinicaltrials.gov ID
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: EU-COAST STUDY: European cost of asthma treatment economic impact of asthma control
Trial description: The economic cost of asthma is considerable both in terms of direct medical costs (such as the cost of pharmaceuticals and hospital admissions) and indirect medical costs (such as time lost from work and premature death).The costs of asthma depend on the severity of disease and the extent to which exacerbations are avoided. Moreover, poor control of asthma symptoms is a major issue that can result in adverse clinical and economic outcomes. According to GINA guidelines, the goal of asthma treatment is to achieve and maintain asthma control. Such an objective can be reached in a majority of patients with a pharmacologic intervention strategy developed in partnership between the patient/family and the doctor. Validated measures for assessing asthma control score goals as continuous variables and provide numerical values to distinguish different levels of control. Among them, the Asthma Control Test (TM - QualityMetric Incorporated) is widely recognized. Few data exist on the relationship between asthma control and health care consumption.Some models for predicting asthma costs have been proposed. However, these models only attempt to assess costs associated with medications and/or asthma exacerbations. Furthermore, in such studies, asthma control was not defined accordingly to current international criteria.Considering the increasing interest of health authorities in reducing asthma associated costs and improving quality of care, it appears necessary to study the relationship between the cost and the level of control.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
health care costs related to asthma according to the patients’ asthma control level
Timeframe: 1 year
Secondary outcomes:
Direct costs and indirect costs of consumed resources
Timeframe: 1 year
Costs directly associated with asthma care and costs associated with asthma complications (exacerbations);
Timeframe: 1 year
Healthcare costs related to asthma (by control) and concomitant diseases
Timeframe: 1 year
Interventions:
Enrollment:
2752
Primary completion date:
Not applicable
Observational study model:
Cohort
Time perspective:
Retrospective
Clinical publications:
Not applicable
- Adult outpatients, male or female aged ≥ 18 ;
- Patient diagnosed with asthma for at least 12 months and at least one antiasthmatic treatment in the last 12 months;
- Patient already included in this study;
- Patient who participated into a clinical trial during the last 6 months;
Inclusion and exclusion criteria
Inclusion criteria:
- Adult outpatients, male or female aged ≥ 18 ;
- Patient diagnosed with asthma for at least 12 months and at least one antiasthmatic treatment in the last 12 months;
- Patient has read the information letter and the informed consent (if applicable).
Exclusion criteria:
- Patient already included in this study;
- Patient who participated into a clinical trial during the last 6 months;
- Patient aged >=45 with an history of smoking of at least 20 packs-year;
- Patient with a chronic obstructive bronchopneumopathy
- Pregnant women.
Trial location(s)
Study documents
No study documents available.
Results overview
No study documents available
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
2010-31-12
Plain language summaries
Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.
Additional information about the trial
Not applicable
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