Last updated: 11/03/2018 12:03:24

The expression of antigens in bone marrow samples from volunteering donors.

GSK study ID
111684
See study documents
Clinicaltrials.gov ID
NCT00706199
EudraCT ID
Not applicable
EU CT Number
Not applicable
Trial status
Study complete
Study complete
Overview
Eligibility
Locations
Study documents
Results summary
Plain language summaries
Additional information

Trial overview

Official title: Analysis of expression of antigens in bone marrow samples from volunteering donors.
Trial description: Antigen expression levels in bone marrow from volunteering donors will be analyzed. The results of this analysis will be used to establish a clinical test to identify cancer patients who could qualify to receive an investigational treatment being developed by GlaxoSmithKline.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:

Number of copies of Wilms’ Tumor 1 (WT1) antigen expression in bone marrow

Timeframe: At Day 0

Number of copies of PRAME (Preferentially expressed in melanoma)antigen expression in bone marrow

Timeframe: At Day 0

Secondary outcomes:
Not applicable
Interventions:
  • Procedure/surgery: Bone marrow aspiration
    • Enrollment:
    48
    Primary completion date:
    2009-23-01
    Observational study model:
    Not applicable
    Time perspective:
    Not applicable
    Clinical publications:
    Not applicable
    Medical condition
    Cancer
    Product
    GSK1711805A
    Collaborators
    Not applicable
    Study date(s)
    July 2008 to January 2009
    Type
    Observational
    Phase
    Not applicable

    Participation criteria

    Sex
    Female & Male
    Age
    18+ years
    Accepts healthy volunteers
    Yes
    • Inclusion Criteria:
    • The donor is aged >= 18 years
    Inclusion and exclusion criteria
    Inclusion criteria:
    • Inclusion Criteria:
    • The donor is aged >= 18 years
    • Written informed consent has been obtained prior to the performance of any specific procedure.
    • The donor has a medical indication for which a bone marrow aspiration is planned.
    • The donor is eligible for a bone marrow aspiration.

    Trial location(s)

    Location
    Status
    Contact us
    Contact us
    Location
    GSK Investigational Site
    Ottignies, Belgium, 1340
    Status
    Study Complete
    Contact us

    Study documents

    Scientific result summary
    Available language(s): English
    Download document(s)

    If you wish to request for full study report, please contact - [email protected]

    Results overview

    Refer to study documents

    Recruitment status
    Study complete
    Actual primary completion date
    2009-23-01
    Actual study completion date
    2009-23-01

    Plain language summaries

    Not applicable. GSK’s transparency policy provides for Plain Language Summaries for Interventional studies.

    Additional information about the trial

    Not applicable
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