Carvedilol Prospective Randomized Cumulative Survival Trial.

A comparative analysis of the results from 4 trials of beta-blocker therapy for heart failure: best, cibis-ii, merit-hf, and copernicus. Domanski, M. J., Krause-Steinrauf, H., Massie, B. M., Deedwania, P., Follmann, D., Kovar, D., Murray, D., Oren, R., Rosenberg, Y., Young, J., Zile, M., and Eichhorn, E. J Card Fail 2003; 9(5):354-63

Beta blockers in heart failure therapy with special reference to the copernicus study]: betablocker in der herzinsuffizienztherapie unter besonderer berucksichtigung der copernicus-studie. Hartmann, F. and Katus, H. A. Herz 2002; 27 Suppl 1(30-4)

Capricorn and coperinus studies]: Etudes capricorn et copernicus. Juilliere, Y. Arch Mal Coeur Vaiss 2002; 95 Spec 4(5 Spec 4):17-20

Carvedilol prospective randomized cumulative survival (copernicus) trial: carvedilol as the sun and center of the beta-blocker world? Wollert, K. C. and Drexler, H. Circulation 2002; 106(17):2164-6

Carvedilol prospective randomized cumulative survival (copernicus) trial: carvedilol in severe heart failure. Fowler, M. B. Am J Cardiol 2004; 93(9A):35B-9B

Carvedilol reduces the costs of medical care in severe heart failure: an economic analysis of the copernicus study applied to the united kingdom. Stewart, S, McMurray, J J, Hebborn, A, and Coats, A J 74th Annual Scientific Sessions American Heart Association 11/11/2001 Anaheim, CA; USA

Carvedilol reduces the costs of medical care in severe heart failure: an economic analysis of the copernicus study applied to the united kingdom. Stewart, S., McMurray, J. J., Hebborn, A., Coats, A. J., and Packer, M. Int J Cardiol 2005; 100(1):143-9

Changes of inflammatory cytokines and uric acid in patients with severe chronic heart failure: a copernicus substudy. Coats, Andrew JS, Katus, Hugo A., Fowler, Michael B., Anker, Stefan D., Bolger, Aidan P., and Packer, Milton 53rd Annual Scientific Session of the American College of Cardiology 3/7/2004 New Orleans, LA; USA

Copernicus (carvedilol prospective randomized cumulative survival trial). a multicenter randomized double-blind, placebo-controlled study to determine the effect of carvedilol on mortality in severe congestive heart failure. Packer, M, Fowler, M, Rouleau, J, Tendera, M, Castaigne, A, Katus, H, Mohacse, P, Coats, A, Shusterman, N, and Staiger, C 8th International Congress on Cardiovascular Pharmacotherapy 3/28/1999 Amsterdam; Netherlands

Copernicus (carvedilol prospective randomized cumulative survival trial). a multicenter randomized double-blind, placebo-controlled study to determine the effect of carvedilol on mortality over 6-45 months in patients with severe congestive heart failure. Packer, M, Fowler, M, Rouleau, J, Tendera, M, Castaigne, A, Katus, H, Mohacse, P, Coats, A, Shusterman, N, and Staiger, C Heart Failure '97: 2nd International Meeting of the Working Group on Heart Failure 5/24/1997 Cologne; Germany

Does the degree of interference with the renin-angiotensin system influence the response to b- blockade in chronic heart failure? results of the copernicus study. Paul Mohacsi, Henry Krum Jean L. Rouleau Michael B. Fowler Hugo A. Katus Andrew J. Coats Michal Tendera Ildiko Amann-Zalan Ellen B. Roecker Milton Packer 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Effect of carvedilol in black patients with severe chronic heart failure: results of the copernicus study. Carson, P, Fowler, M B, Mohacsi, Krum, H, Tendera, M, Coats, A J, Rouleau, J L, Holcslaw, T, Staiger, C, Roecker, E B, Amann-Zalan, I, and Packer, M 74th Annual Scientific Sessions American Heart Association 11/11/2001 Anaheim, CA; USA

Effect of carvedilol on clinical status early following initiation of therapy in patients with severe chronic heart failure: results of the copernicus study. Kruml, AJS Coats MB Fowler HA Katus P Mohasci- JL Rouleau M Tendera He Copernicus Study Group 14th World Congress of Cardiology 5/5/2002 Sydney; Australia

Effect of carvedilol on global assessment of patients with severe chronic heart failure: the copernicus study. 1. Amann-Zalanl, M. Tendera M. Packer M. B. Fowler H. A. Katus- H. Krum P. Mohacsi J-1. Rouleau A. Castaigne A. J. S. Coats 23rd Annual Congress of the European Society of Cardiology Together with the 36th Annual General Meeting of the Association for European Paediatric Cardiology 9/1/2001 Stockholm; Sweden

Effect of carvedilol on hospitalization in patients with severe chronic heart failure: results of the copernicus study. Amann-Zalanl, A. J. S. Coats M. B. Fowler H. A. Katus H. Krum- P. Mohacsi J-1. Rouleau M. Tendera M. Packer P. Carson 23rd Annual Congress of the European Society of Cardiology Together with the 36th Annual General Meeting of the Association for European Paediatric Cardiology 9/1/2001 Stockholm; Sweden

Effect of carvedilol on major clinical events in patients with severe heart failure and an extremely depressed ejection fraction: results of the copernicus study. Hugo A. Katus, Michal Tendera Paul Mohacsi Jean L. Rouleau Michael B. Fowler Andrew J. Coats Henry Krum Terry L. Holcslaw Ellen B. Roecker Milton Packer for the COPERNICUS Study Group. 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Effect of carvedilol on patients well-being in severe chronic heart failure: results of the copernicus study. Tendera, M, Mohacsi, P J, Krum, H, Coats, A J S, Fowler, M B, Rouleau, J L, Castaigne, A, Amman-Zalan, I, Packer, M, and Holcslaw, T C Heart Failure Update 2002: From Damage to Defence 6/8/2002 Oslo; Norway

Effect of carvedilol on patients' well-being in severe chronic heart failure: results of the copernicus study. Tendera, M, Mohacsi, P, Krum, H Fowler M B, Coats, A J, Rouleau, J L, Castaigne, A, Amann-Zalan, I, Staiger, C, Holcslaw, T, Roecker, E B, and Packer, M 74th Annual Scientific Sessions American Heart Association 11/11/2001 Anaheim, CA; USA

Effect of gender on the outcome of patients with severe heart failure treated with carvedilol: results of the copernicus study. Michal P. Tendera, Andrew J. Coats Michael B. Fowler Hugo A. Katus Paul Mohacsi Jean L. Rouleau Henry Krum Ildiko Amann-Zalan Neil H. Shusterman Ellen B. Roecker Milton Packer for the COPERNICUS Study 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Efficacy and safety of carvedilol during initiation of therapy in patients with severe chronic heart failure: results of the copernicus study. E.B. Roeckerl, H. Krum A. J. S. Coats H. A. Katus P. Mohacsi- J. 1. Rouleau6 M. Tendera M. Packer the COPERNICUS Study Group 24th Annual Congress of the European Society of Cardiology 8/31/2002 Berlin; Germany

Efficacy and safety of carvedilol in patients with low systolic blood pressure in the copernicus study. J.-. Rouleaul, H. Krum H. A. Katus A. J. S Coats M. Tendera- P. Mohacsi E. B. Roecker M. Packer the COPERNICUS Study Group 24th Annual Congress of the European Society of Cardiology 8/31/2002 Berlin; Germany

Efficacy and safety of carvedilol in patients with severe chronic heart failure and low systolic blood pressure: results of the copernicus study. Jean L. Rouleau, Michael B. Fowler Henry Krum Hugo A. Katus Andrew J. Coats Michal Tendera Paul Mohacsi Ildiko Amann-Zalan Terry L. Holcslaw Ellen B. Roecker Milton Packer 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Efficacy and safety of initiating carvedilol in patients with severe chronic heart failure: results of the copernicus study. Krum, H, Mohacsi, P, Roecker, E B, Rouleau, J L, Tendera, M, Katus, H A, Fowler, M B, Lukas, M A, Packer, M, and COPERNICUS Study Group 75th Annual Scientific Sessions of the American Heart Association 11/17/2002 Chicago, IL; USA

Haemoglobin level is associated wtih adverse outcomes in patients with severe chronic heart failure: results from the copernicus study. Anker, S. D, Mohacsi, P, Coats, A. J. S, Roecker, E. B, Rouleau, J-L., Krum, H., Scherhag, A, and Packer, M. 25th Annual Congress of the European Society of Cardiology 8/30/2003 Vienna; Austria

Hemoglobin level is associated with mortality and hospitalization in patients with severe chronic heart failure: results from the copernicus study. Anker, Stefan D., Coats, Andrew JS, Roecker, Ellen B., Mohacsi, Paul, Rouleau, Jean, Scherhag, Armin, Krum, Henry, and Packer, Milton 53rd Annual Scientific Session of the American College of Cardiology 3/7/2004 New Orleans, LA; USA

Impact of additional neurohormonal (nh) antagonism in severe chf patients already receiving a combination of nh antagonists in copernicus. H. Kruml, M. B. Fowler H. A. Katus P. Mohasci J. 1. Rouleau- M. Tendera E. B. Roecker M. Packer the COPERNICUS Study Group 24th Annual Congress of the European Society of Cardiology 8/31/2002 Berlin; Germany

Is additional neurohormonal antagonism useful in patients with severe chronic heart failure already receiving a combination of neurohormonal antagonists? results of the copernicus study. Henry Krum, Paul Mohacsi Hugo A. Katus Michal Tendera Jean L. Rouleau Michael B. Fowler Andrew J. Coats Ellen B. Roecker Milton Packer 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Mechanisms contributing to the effect of carvedilol in severe heart failure: results of the copernicus study. P. carson, C. 0Connor V. Bernstein M. Haass V. Mareev- A. Miller S. Perrone B. Rauch G. Sutton M. Packerl 23rd Annual Congress of the European Society of Cardiology Together with the 36th Annual General Meeting of the Association for European Paediatric Cardiology 9/1/2001 Stockholm; Sweden

Nt-probnp in severe chronic heart failure: rationale, design and preliminary results of the copernicus nt-probnp substudy. Hartmann, F., Packer, M., Coats, A. J., Fowler, M. B., Krum, H., Mohacsi, P., Rouleau, J. L., Tendera, M., Castaigne, A., Trawinski, J., Amann-Zalan, I., Hoersch, S., and Katus, H. A. Eur J Heart Fail 2004; 6(3):343-50

Packer M., Coats A. J.S., Fowler M. B., Katus H. A., Krum H., Mohacsi P., Rouleau J. L., Tendera M., Castaigne A., Roecker E. B., Schultz M. K., Staiger C., Curtin E. L., DeMets D. L., The Carvedilol Prospective Randomized Cumulative Survival Study Group N Engl J Med 2001; 344:1651-1658, May 31, 2001.

Plasma n-terminal pro-bnp predicts the occurrence of major clinical events in severe chronic heart failure: results of a substudy of the copernicus trial. Franz S. Hartmann, Gert Richardt Milton Packer Andrew J. Coats Michael B. Fowler Henry Krum Paul Mohacsi Jean L. Rouleau Michal Tendera Alain Castaigne Matthias Baumann Juergen Trawinski Silke Horsch Ildiko Amann-Zalan Hugo A. Katus 51st Annual Scientific Sessions of the American College of Cardiology 3/17/2002 Atlanta, GA; USA

Prevention and reversal of cardiac cachexia in patients with severe heart failure by carvedilol: results of the copernicus study. Coats, A J, Anker, S D, Roecker, E B, Schultz, M K, Staiger, C, Amann-Zalan, I, Shusterman, N, and Packer, M 74th Annual Scientific Sessions American Heart Association 11/11/2001 Anaheim, CA; USA

Primary results of copernicus, a pivotal landmark study (carvedilol prospective randomised cumulative survival trial). Cardiovasc J S Afr 2001; 12(1):57

Safety and tolerability of carvedilol in patients with severe chronic heart failure: results of the copernicus study. Krum, H, Coats, A J, Fowler, M B, Mohacsi, P, Rouleau, J L, Tendera, M, Roecker, E B, Amann-Zalan, I, Staiger, C, Holcslaw, T, and Packer, M 74th Annual Scientific Sessions American Heart Association 11/11/2001 Anaheim, CA; USA

Safety and tolerability of carvedilol in patients with severe chronic heart failure: the copernicus study. H. Kruml, A. Coats M. Fowler H. Katus p. Mohacsi- J. Rouleau M. Tendera A. Castaigne 1. Amann-Zalan M. Packerl 23rd Annual Congress of the European Society of Cardiology Together with the 36th Annual General Meeting of the Association for European Paediatric Cardiology 9/1/2001 Stockholm; Sweden

The carvedilol prospective randomized cumulative survival (copernicus) trial. Eichhorn, E. J. and Bristow, M. R. Curr Control Trials Cardiovasc Med 2001; 2(1):20-23

The effects of betablockers on mortality/morbidity in patients with chf. Hjalmarson, Ã ke 2 and Kitakaze, Masafumi 69th Annual Scientific Meeting of the Japanese Circulation Society 3/19/2005 Tokyo; Japan

The prognostic significance of nt-probnp in severe chronic heart failure is independent of aetiology: a substudy of the copernicus trial. F. Hartmann, M. Packer A. J. Coats p. Mohacsi M. Tendera-. Amann-Zalan M. Baumann H. A. Katusl The COPERNICUS Study Group 24th Annual Congress of the European Society of Cardiology 8/31/2002 Berlin; Germany