Last updated: 11/07/2018 01:07:18
A study to investigate the effect of renal insufficiency on the pharmacokinetics of carvedilol and the metabolites of carvedilol after single and multiple dose administration in patients with hypertension.
Clinicaltrials.gov ID
Not applicable
EudraCT ID
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EU CT Number
Not applicable
Trial status
Study complete
Study complete
Trial overview
Official title: A study to investigate the effect of renal insufficiency on the pharmacokinetics of carvedilol and the metabolites of carvedilol after single and multiple dose administration in patients with hypertension.
Trial description: A study to investigate the effect of renal insufficiency on the pharmacokinetics of carvedilol and the metabolites of carvedilol after single and multiple dose administration in patients with hypertension.
Primary purpose:
Not applicable
Trial design:
Not applicable
Masking:
Not applicable
Allocation:
Not applicable
Primary outcomes:
Not applicable
Secondary outcomes:
Not applicable
Interventions:
Not applicable
Enrollment:
Not applicable
Primary completion date:
Not applicable
Observational study model:
Not applicable
Time perspective:
Not applicable
Clinical publications:
Gehr TWB, Tenero DM, Boyle DA, Sica D, & Shusterman NH. The pharmacokinetics of carvedilol and its metabolites after single and multiple dose oral administration in patients with hypertension and renal insufficiency. Eur J Clin Pharmacol 1999;55:269-277.
Tenero D, Boyle D, McSurdy-Freed J, Shusterman N, Krug-Gourley S, & Gehr T. Pharmacokinetics of carvedilol and its enantiomers in patients with renal insufficiency. Pharmacotherapy 1995;15(3):393.
Medical condition
Hypertension
Product
carvedilol
Collaborators
Not applicable
Study date(s)
May 1991 to June 1993
Type
Not applicable
Phase
2
Participation criteria
Sex
Not applicable
Age
Not applicable
Accepts healthy volunteers
Not applicable
Inclusion and exclusion criteria
Trial location(s)
This study does not involve prospective enrollment of participants.
Study documents
Scientific result summary
Available language(s): English
If you wish to request for full study report, please contact - [email protected]
Results overview
Not applicable
Recruitment status
Study complete
Actual primary completion date
Not applicable
Actual study completion date
1993-23-06
Plain language summaries
Plain language summaries of clinical trial results for Phase 2-4 clinical trials that were initiated on or after January 2022 will be posted by GSK within one year following study completion.
Additional information about the trial
Not applicable
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