Completed

Study Description:

This is a retospective observational study that will utilize pharmaceutical and medical claims from the Quebec Provincial Health Insurance administrative databases. All patients with a diagnosis of asthma that have been treated with fluticasone propionate/salmeterol combination or fluticasone propionate monotherapy between January 01, 2001 and March 31, 2011 will be included in the asthma cohort. Patients will be followed from the time of entry in the cohort through March 31, 2011, death or withdrawal from the insurance plan whichever occurs first. The study assesses the association between adherence to treatment and asthma related health care resource utilization in patients treated with fluticasone propionate/salmeterol combination in a single inhaler (FSC). Adherence to treatment will be determined on the basis of the Medication Possession Ratio and Persistence. Exacerbations will be defined as use of oral corticosteroids, emergency room visits and hospitalizations related to asthma. Health care utilization will include medication use, visits to physicians and clinics and hospitalizations

GSK Study ID:

116914


Has Results Document Available
ClinicalTrials.gov Identifier:

Not Available


EudraCT Number:

Not Available


Study Overview

Medical Conditions

Asthma

Product

fluticasone propionate;fluticasone propionate/salmeterol/norflurane;norflurane;salmeterol

Collaborators

N/A


Date

November 2012 to December 2012

Type

Observational

Phase

N/A


Gender

Both

Age

12 Year+

Accepts Healthy Volunteers

none


Locations


Study Design

  • Primary Purpose: Not Available
  • Allocation: Not Available
  • Study Design: Not Available
  • Study Classification: Not Available
  • Masking: Not Available
  • Masked Subject: Not Available
  • Masked Caregiver: Not Available
  • Masked Investigator: Not Available
  • Masked Assessor: Not Available
Primary Outcomes:

  • Asthma-related healthcare resource utilization
    Timeframe: January 01, 2001 to March 31, 2011

  • Asthma-related exacerbations
    Timeframe: January 01, 2001 to March 31, 2011

Interventions:

  • drug: fluticasone propionate
  • drug: Salmeterol and fluticasone propionate combination
Inclusion / Exclusion Criteria: Click to view inclusion/exclusion criteria:
Enrollment: 0

Clinical Publications:

  • Afisi Ismaila, Diane Corriveau, Julie Vaillancourt, Daria Parsons, Richard Stanford, Zhen Su, John Sampalis.Impact of adherence to treatment with fluticasone propionate / salmeterol in asthma patients.Curr Med Res Opin.2014;30(7):1417-25
  • Afisi Ismaila, Diane Corriveau, Julie Vaillancourt, Daria Parsons, Richard Stanford, Zhen Su, John Sampalis.Impact of adherence to treatment with fluticasone propionate / salmeterol in asthma patients.Curr Med Res Opin.2014