.main-title {
    font-size: 1.625rem;
    font-weight: 400;
    color: #f36533;
    margin-bottom: 0.625rem; }
@media screen and (min-width: 48em) {
    .main-title {
        font-size: 2.5rem; } }

.hd-2 {
    font-size: 1.625rem;
    font-weight: 400;
    color: #f36533; }
@media screen and (min-width: 48em) {
    .hd-2 {
        font-size: 2.5rem; } }

.hd-1 {
    font-size: 1.875rem;
    font-weight: 400;
    color: #f36533; }

.hd1 {
    font-size: 1.875rem;
    font-weight: 700;
    color: #f36533; }

.hd2 {
    font-size: 1.125rem;
    font-weight: 700;
    color: #f36533;
    margin-bottom: 1.25rem; }

.hd3 {
    font-family: Arial, Helvetica, sans-serif;
    font-size: 1rem;
    font-weight: 700;
    color: #544f40; }

.sub-title {
    font-family: Arial, Helvetica, sans-serif;
    font-size: 1.375rem;
    font-weight: 700;
    color: #544f40; }

.studies-title {
    font-family: Arial, Helvetica, sans-serif;
    font-size: 1.125rem;
    font-weight: 700;
    color: #544f40; }

.search-status {
    background-color: #f5f5f5;
    padding: 0.3125rem 0.625rem; }
.search-status strong {
    margin-right: 1rem;
    color: #544f40; }
.search-status .text-search p,
.search-status .text-search span,
.search-status .text-search a,
.search-status .more-option p,
.search-status .more-option span,
.search-status .more-option a {
    display: inline-block;
    margin: 0 auto;
    font-size: 0.875rem; }
.search-status .text-search .btn-accordion-panel.show .icon-fa {
    background-image: url(../img/up-minus.png); }

.plus.icon {
    color: #000;
    position: absolute;
    margin-left: 3px;
    margin-top: 10px; }

.plus.icon:before {
    content: '';
    position: absolute;
    width: 10px;
    height: 3px;
    background-color: currentColor; }

.plus.icon:after {
    content: '';
    position: absolute;
    width: 10px;
    height: 3px;
    background-color: currentColor;
    -webkit-transform: rotate(90deg);
    transform: rotate(90deg); }

.minus.icon {
    color: #000;
    position: absolute;
    margin-left: 3px;
    margin-top: 10px;
    width: 10px;
    height: 3px;
    background-color: currentColor; }

.sub-hd1 {
    font-size: 1.875rem;
    color: #f36533;
    margin: 0 0 0.625rem; }

.mr-t13 {
    margin-top: 0.8125rem !important; }

.scrollup {
    opacity: 1;
    position: fixed;
    bottom: 5%;
    right: 5%;
    display: none;
    z-index: 99; }
@media screen and (min-width: 48em) {
    .scrollup {
        right: 1%;
        bottom: 15.63rem; } }
@media screen and (max-width: 736px) and (orientation: landscape) {
    .scrollup {
        bottom: 15%; } }
@media screen and (min-width: 75em) {
    .scrollup {
        right: 2%;
        bottom: 15.63rem; } }
.scrollup i {
    width: 40px;
    height: 40px;
    background: url("../img/icon_arrowtop-h.png") no-repeat;
    display: block;
    margin: 0 auto 0.0625rem; }
.scrollup strong {
    display: none;
    color: #4a4a4a; }
@media screen and (min-width: 48em) {
    .scrollup strong {
        display: block; } }
.scrollup:hover i {
    background: url("../img/icon_arrowtop.png") no-repeat; }
.scrollup:hover strong {
    color: #f36533; }

.accordion-panel {
    font-size: 0.875rem; }
.accordion-panel p {
    margin-bottom: 0.5rem; }

.w-16 {
    min-width: 16% !important; }

html {
    -moz-osx-font-smoothing: grayscale;
    -webkit-font-smoothing: antialiased; }

body {
    margin: 0;
    padding: 0;
    font-family: Arial, Helvetica, sans-serif; }

a {
    color: #f36533; }

a:hover {
    text-decoration: none; }

input:focus,
button:focus,
a:focus {
    outline-width: 0;
    outline-style: solid;
    outline-color: transparent; }

button:focus,
a:focus {
    border: 0;
    outline: none; }

img {
    max-width: 100%; }

.download-pdf {
    display: block;
    color: #15717d;
    background: #FFF;
    padding: 0.5625rem 2.813rem 0.5625rem 0.625rem;
    position: relative;
    margin-bottom: 0.625rem; }
.download-pdf i {
    width: 2.5rem;
    height: 100%;
    background: url(../img/icon-pdf@2x.png) #f36533 no-repeat center center;
    background-size: 26px 26px;
    position: absolute;
    right: 0;
    top: 0;
    border-left: solid 1px #f36533; }
.download-pdf:visited {
    color: #15717d;
    background: #FFF; }
.download-pdf:visited i {
    background: url(../img/icon-pdf@2x.png) #f36533 no-repeat center center;
    border-left: solid 1px #f36533; }
.download-pdf:hover, .download-pdf:focus {
    color: #FFF;
    background-color: #f36533; }
.download-pdf:hover i, .download-pdf:focus i {
    border-left: solid 1px #FFF; }
.download-pdf.pdf-gray {
    background-color: #f5f5f5;
    font-size: 1.125rem; }
.download-pdf.pdf-gray:hover, .download-pdf.pdf-gray:focus {
    color: #FFF;
    background-color: #f36533; }
.download-pdf.pdf-gray:hover i, .download-pdf.pdf-gray:focus i {
    border-left: solid 1px #FFF; }

.menu-filter .search-btn,
.menu-filter .reset-btn {
    margin: 0 14px;
    padding: 9px 6px;
    font-size: 0.875rem;
    background-color: #f36533;
    padding: 0.3125rem 0.3125rem;
    color: #FFF;
    text-transform: capitalize;
    font-size: 12px; }

header {
    z-index: 9;
    position: relative;
    -webkit-transition: all 0.5s ease;
    -moz-transition: position 10s;
    -ms-transition: position 10s;
    -o-transition: position 10s;
    transition: all 0.5s ease; }
@media screen and (min-width: 36em) {
    header {
        margin-bottom: 0.9375rem; } }
header .navbar {
    padding-left: 0;
    padding-right: 0; }
@media screen and (min-width: 36em) {
    header .navbar {
        padding-left: 1rem;
        padding-right: 1rem; } }
header .navbar .container {
    padding-left: 0.9375rem;
    padding-right: 0.9375rem;
    position: relative;
    width: 100%;
    max-width: 100%; }
@media screen and (min-width: 75em) {
    header .navbar .container {
        max-width: 71.25rem; } }
@media screen and (min-width: 36em) {
    header .navbar {
        padding-left: 0;
        padding-right: 0; } }
header.header-fixed {
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    animation: smoothScroll 0.5s forwards;
    z-index: 9999;
    border-bottom: solid 1px #f36533; }
header.header-fixed .navbar .navbar-brand {
    position: absolute;
    z-index: 2;
    top: 0;
    left: 0.9375rem;
    padding: 2px 0 0.125rem 0.625rem; }
@media screen and (min-width: 62em) {
    header.header-fixed .navbar .navbar-brand {
        padding: 0.9375rem 0 0.9375rem 0.625rem; } }
header.header-fixed .top-submenu {
    margin-top: 0; }
@media screen and (min-width: 62em) {
    header.header-fixed .top-submenu {
        margin-top: 0.9375rem; } }
@media screen and (min-width: 62em) {
    header.header-fixed .top-submenu .navbar-nav .nav-item {
        padding: 0 0.5rem; } }
@media screen and (min-width: 62em) {
    header.header-fixed .top-submenu .navbar-nav .nav-item.top-nav-item {
        padding: 0 0.5rem; } }
header.header-fixed .top-submenu .navbar-nav .nav-item .nav-link {
    padding: 0; }
header.header-fixed .top-submenu .navbar-nav .nav-item .nav-link:hover {
    color: #f36533; }
header.header-fixed .main-nav .main-nav-container {
    margin-left: 0;
    background-color: #f36533; }
@media screen and (min-width: 62em) {
    header.header-fixed .main-nav .main-nav-container {
        background-color: #FFF;
        margin-left: 70px; } }
header.header-fixed .main-nav .main-nav-container .navbar-collapse {
    border-top: 0;
    background-color: #f36533; }
@media screen and (min-width: 62em) {
    header.header-fixed .main-nav .main-nav-container .navbar-collapse {
        background-color: #FFF; } }
header.header-fixed .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link {
    color: #FFF; }
@media screen and (min-width: 62em) {
    header.header-fixed .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link {
        padding: 0.3125rem 0.375rem;
        color: #4a4a4a; } }
header.header-fixed .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item:first-child {
    display: none; }
header .bg-white {
    background-color: #FFF; }
header .navbar-brand img {
    max-width: 2.375rem; }
@media screen and (min-width: 62em) {
    header .navbar-brand img {
        max-width: 3.125rem; } }
header .top-submenu {
    font-family: Arial, Helvetica, sans-serif;
    font-size: 0.75rem;
    color: #4a4a4a; }
@media screen and (min-width: 75em) {
    header .top-submenu {
        font-size: 0.875rem; } }
header .top-submenu .navbar-nav {
    display: -ms-flexbox;
    display: flex;
    -ms-flex-direction: row;
    flex-direction: row; }
header .top-submenu .nav-item {
    padding: 0.625rem 0.3125rem;
    position: relative;
    border-right: solid 0.0625rem #d5d1ce;
    padding-left: 0.9375rem;
    padding-right: 0.9375rem; }
@media screen and (min-width: 62em) {
    header .top-submenu .nav-item {
        border-left: solid 0.0625rem #d5d1ce;
        border-right: 0;
        padding: 1.188rem 0.5rem; } }
header .top-submenu .nav-item.top-nav-item {
    display: none; }
@media screen and (min-width: 62em) {
    header .top-submenu .nav-item.top-nav-item {
        display: inline; } }
header .top-submenu .nav-item.search-toggle span {
    display: none; }
@media screen and (min-width: 48em) {
    header .top-submenu .nav-item.search-toggle span {
        display: inline; } }
header .top-submenu .nav-item.contact-us span {
    display: none; }
@media screen and (min-width: 48em) {
    header .top-submenu .nav-item.contact-us span {
        display: inline; } }
header .top-submenu .nav-item .nav-link {
    color: #544f40; }
header .top-submenu .nav-item .nav-link i {
    width: 15px;
    display: inline-block;
    vertical-align: top;
    margin-right: 0.1875rem; }
header nav:first-child {
    border-bottom: solid 1px #d5d1ce; }
@media screen and (min-width: 62em) {
    header nav:first-child {
        border-bottom: 0; } }
header .navbar .navbar-brand {
    margin-right: 0;
    padding: 0.9375rem 0 0.9375rem 0.9375rem; }

@keyframes smoothScroll {
    0% {
        transform: translateY(-60px); }
    100% {
        transform: translateY(0px); } }
@keyframes smoothScroll-x {
    0% {
        transform: translateY(10px); }
    100% {
        transform: translateY(0px); } }
.search-container {
    position: relative;
    -moz-transition: all 0.3s;
    -o-transition: all 0.3s;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
    height: 0;
    z-index: 9;
    right: 0;
    display: none; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .search-container {
        position: relative;
        -moz-transition: all 0.3s;
        -o-transition: all 0.3s;
        -webkit-transition: all 0.3s;
        transition: all 0.3s;
        height: 0;
        z-index: 9;
        right: 0; } }
.search-container.opened {
    transform: translateZ(0);
    transition: all 0.5s;
    animation-direction: normal;
    animation-duration: 0.3s;
    display: block;
    min-height: 75px;
    background-color: #f5f5f5;
    border-bottom: solid 0.125rem #f36533;
    position: fixed;
    left: 0;
    right: 0;
    top: 0;
    padding: 5px 0; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .search-container.opened {
        transform: translateZ(0);
        transition: all 0.5s;
        animation-direction: normal;
        animation-duration: 0.3s;
        display: block;
        min-height: 75px;
        background-color: #f5f5f5;
        border-bottom: solid 0.125rem #f36533;
        position: fixed;
        left: 0;
        right: 0;
        top: 0;
        padding: 5px 0; } }
.search-container input[type="text"] {
    outline: none;
    background-color: #f5f5f5;
    border: 0;
    padding-left: 2rem;
    border-radius: 0;
    height: 64px;
    font-size: 1.5rem;
    font-weight: 700; }
.search-container input[type="text"]:focus {
    box-shadow: none; }
.search-container .search-icon {
    vertical-align: middle;
    position: absolute;
    left: 0;
    top: 50%;
    height: 2.125rem;
    width: 2.125rem;
    background-color: transparent;
    border: 0;
    padding: 4px;
    margin-top: -17px; }
.search-container .search-icon img {
    display: block; }
.search-container .close-icon {
    cursor: pointer;
    position: absolute;
    right: 6px;
    top: 50%;
    width: 2.125rem;
    background-color: transparent;
    border: 0;
    padding: 0.625rem;
    background-image: url(../img/close-2.png);
    height: 22px;
    width: 22px;
    margin-top: -11px;
    background-repeat: no-repeat; }
.search-container .close-icon:hover, .search-container .close-icon:focus {
    background-image: url(../img/close-1.png); }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .search-container .close-icon {
        cursor: pointer;
        position: absolute;
        right: 6px;
        top: 50%;
        width: 2.125rem;
        background-color: transparent;
        border: 0;
        padding: 0.625rem;
        background-image: url(../img/close-2.png);
        height: 22px;
        width: 22px;
        margin-top: -11px;
        background-repeat: no-repeat; }
    .search-container .close-icon:hover, .search-container .close-icon:focus {
        background-image: url(../img/close-1.png); } }

.ie10 header .top-submenu .nav-item.top-nav-item {
    display: block;
    float: left; }
.ie10 header .top-submenu .nav-item {
    display: block;
    float: left; }

@supports (-ms-ime-align: auto) {
    .search-container form input::-ms-clear {
        display: none; } }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .search-container form input[type=text]::-ms-clear {
        display: none; } }
.footer-wrapper {
    border-top: solid 1px #59595b;
    padding-top: 2.25rem;
    margin-bottom: 0.625rem; }
.footer-wrapper .gsk-logo {
    max-width: 3.25rem;
    display: block;
    margin: 0 auto 0.9375rem; }
@media screen and (min-width: 75em) {
    .footer-wrapper .gsk-logo {
        display: block;
        max-width: 100%; } }

.gsk-logo {
    background-size: contain;
    display: block; }

@media screen and (min-width: 75em) {
    .footer-social {
        float: right;
        text-align: right; } }
.footer-social ul {
    margin: 0 0 0.9375rem;
    padding: 0;
    text-align: center; }
@media screen and (min-width: 75em) {
    .footer-social ul {
        margin: 0;
        padding: 0; } }
.footer-social ul li {
    display: inline-block;
    margin: 0 0 0 0.3125rem;
    padding: 0;
    vertical-align: middle; }
@media screen and (min-width: 36em) {
    .footer-social ul li {
        margin: 0 0.625rem; } }
.footer-social ul li:first-child {
    margin: 0; }
.footer-social ul li a {
    display: block;
    width: 1.75rem;
    height: 1.75rem;
    color: rgba(74, 74, 74, 0.7); }
.footer-social ul li a svg {
    display: block;
    width: 1.75rem;
    height: 1.75rem;
    fill: rgba(74, 74, 74, 0.7); }
.footer-social ul li a:hover {
    color: #f36533; }
.footer-social ul li a:hover svg {
    fill: #f36533; }
.footer-social ul li a i {
    font-size: 1.75rem; }

.footer-links ul {
    padding: 0;
    margin: 0 0 0.625rem;
    list-style: none; }
.footer-links ul li {
    text-align: center; }
@media screen and (min-width: 48em) {
    .footer-links ul li {
        text-align: left; } }
@media screen and (min-width: 75em) {
    .footer-links ul li {
        text-align: left; } }
.footer-links ul li a {
    font-size: 0.875rem;
    color: #1f1f1f; }
.footer-links ul li a:hover {
    color: #f36533; }

.footer-copyright {
    font-size: 0.75rem;
    text-align: center; }
@media screen and (min-width: 75em) {
    .footer-copyright {
        text-align: left; } }
.footer-copyright a {
    color: #4a4a4a; }
.footer-copyright a:hover {
    color: #f36533;
    text-decoration: underline; }

header .main-nav .toggle-button-holder {
    display: flex;
    -ms-flex-wrap: wrap;
    flex-wrap: wrap;
    -ms-flex-align: center;
    align-items: center;
    -ms-flex-pack: justify;
    justify-content: space-between;
    padding-left: 0.9375rem;
    padding-right: 0.9375rem;
    width: 100%; }
@media screen and (min-width: 62em) {
    header .main-nav .toggle-button-holder {
        display: none; } }
header .main-nav .navbar-toggler {
    border-color: rgba(243, 101, 51, 0.2); }
header .main-nav .navbar-toggler .navbar-toggler-icon {
    background-image: url("data:image/svg+xml;charset=utf8,%3Csvg viewBox='0 0 32 32' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath stroke='rgba(243,101,51, 0.7)' stroke-width='2' stroke-linecap='round' stroke-miterlimit='10' d='M4 8h24M4 16h24M4 24h24'/%3E%3C/svg%3E"); }
header .main-nav .main-nav-container {
    position: relative;
    background-color: #f36533;
    width: 100%; }
header .main-nav .main-nav-container .navbar-collapse {
    background-color: #f36533;
    position: absolute;
    left: 0;
    right: 0; }
@media screen and (min-width: 62em) {
    header .main-nav .main-nav-container .navbar-collapse {
        position: relative; } }
header .main-nav .main-nav-container .navbar-collapse .nav-pills {
    display: block; }
@media screen and (min-width: 62em) {
    header .main-nav .main-nav-container .navbar-collapse .nav-pills {
        display: -ms-flexbox;
        display: flex;
        -ms-flex-wrap: wrap;
        flex-wrap: wrap; } }
header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item {
    padding: 0.125rem; }
@media screen and (min-width: 62em) {
    header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item.main-nav-item {
        display: none; } }
header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link {
    color: #FFF;
    border-radius: 0;
    padding: .5rem;
    text-align: left;
    font-size: 0.875rem; }
@media screen and (min-width: 62em) {
    header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link {
        text-align: center;
        font-size: 0.875rem; } }
@media screen and (min-width: 75em) {
    header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link {
        padding: 0.5rem 0.5625rem;
        max-width: 100%;
        font-size: 1rem; } }
header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link.active, header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link:hover {
    background-color: #FFF;
    color: #f36533; }
header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link.icon-home i {
    width: 1.375rem;
    height: 1.5rem;
    background: url(../img/home-white@2x.png) no-repeat center center;
    background-size: contain;
    display: block; }
@media screen and (min-width: 62em) {
    header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link.icon-home i {
        margin: 0 auto; } }
header .main-nav .main-nav-container .navbar-collapse .nav-pills .nav-item .nav-link.icon-home:hover i {
    background-image: url(../img/home-orange@2x.png); }
header .main-nav .container {
    padding-left: 0;
    padding-right: 0; }
@media screen and (min-width: 36em) {
    header .main-nav .container {
        padding-left: 0.9375rem;
        padding-right: 0.9375rem; } }

.navbar .main-nav-toggler {
    font-size: 0.875rem;
    color: #f36533;
    border-color: transparent; }
.navbar .main-nav-toggler .navbar-toggler-icon {
    border-color: #f36533;
    background-image: url("data:image/svg+xml;charset=utf8,%3Csvg viewBox='0 0 32 32' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath stroke='rgba(243,101,51, 1)' stroke-width='2' stroke-linecap='round' stroke-miterlimit='10' d='M4 8h24M4 16h24M4 24h24'/%3E%3C/svg%3E"); }

.home-banner {
    position: relative; }
.home-banner .owl-stage {
    transform: translate3d(-2240px, 0px, 0px);
    transition: all 10s ease 0s;
    width: 7840px; }
.home-banner .owl-nav button[class*='owl-'] {
    background-color: #FFF;
    position: absolute;
    top: 34%;
    left: 0;
    margin-top: -1.25rem;
    width: 1.75rem;
    height: 1.75rem;
    text-align: center;
    padding-right: 0.25rem !important;
    border-radius: 50%; }
@media screen and (min-width: 24em) {
    .home-banner .owl-nav button[class*='owl-'] {
        width: 1.75rem;
        height: 1.75rem; } }
@media screen and (min-width: 36em) {
    .home-banner .owl-nav button[class*='owl-'] {
        width: 2.5rem;
        height: 2.5rem; } }
@media screen and (min-width: 48em) {
    .home-banner .owl-nav button[class*='owl-'] {
        left: -1.5rem;
        top: 50%; } }
.home-banner .owl-nav button[class*='owl-'].owl-next {
    padding-right: 0 !important;
    padding-left: 0.25rem !important;
    left: auto;
    right: 0; }
@media screen and (min-width: 48em) {
    .home-banner .owl-nav button[class*='owl-'].owl-next {
        left: auto;
        right: -1.5rem; } }
.home-banner .owl-nav button[class*='owl-'] span {
    display: block;
    text-align: center; }
.home-banner .owl-nav button[class*='owl-'] span .icon-arrow {
    width: 1.125rem;
    height: 1.125rem;
    display: block;
    text-align: center;
    margin: 0 auto; }
.home-banner .owl-nav button[class*='owl-'] span .icon-arrow img {
    max-width: 100%;
    height: 100%;
    vertical-align: top; }

.banner-holder {
    position: relative; }
.banner-holder .slide-content {
    position: relative;
    left: 0;
    bottom: 0;
    padding: 0.9375rem;
    color: #4a4a4a;
    font-weight: 700;
    font-size: 0.8125rem;
    height: 8rem;
    margin: 0 0.9375rem;
    margin-top: -1.875rem;
    background-color: rgba(255, 255, 255, 0.9); }
.banner-holder .slide-content h1,
.banner-holder .slide-content h2 {
    font-size: 24px;
    font-weight: 700; }
@media screen and (min-width: 36em) {
    .banner-holder .slide-content {
        font-size: 1.25rem; } }
@media screen and (min-width: 48em) {
    .banner-holder .slide-content {
        position: absolute;
        left: 0;
        bottom: 0;
        padding: 13% 13% 3% 5%;
        color: #FFF;
        font-weight: 700;
        width: 70%;
        max-width: 32rem;
        font-size: 16px;
        height: 9rem;
        background: url(../img/slide-contbg.png) no-repeat right top;
        width: 50%;
        height: 20.63rem;
        line-height: 1.875rem;
        padding: 8% 8% 1.25rem 3%;
        margin: 0;
        vertical-align: middle; } }
@media screen and (max-width: 48em) {
    .banner-holder .slide-content {
        padding: 5% 5% 1.25rem 2%;
        height: 210px; } }
@media screen and (max-width: 62em) {
    .banner-holder .slide-content {
        font-size: 0.875rem;
        padding: 5% 8% 1.25rem 2%; } }
@media screen and (min-width: 62em) {
    .banner-holder .slide-content {
        height: 20.63rem;
        margin-top: 10%; } }
@media screen and (min-width: 75em) {
    .banner-holder .slide-content {
        height: 25.63rem;
        margin-top: 10%; } }
@media screen and (max-width: 75em) {
    .banner-holder .slide-content {
        line-height: 1.563rem;
        font-size: 1rem; } }

.clinical-study-section {
    margin: 2.625rem 0 2.188rem 0; }
.clinical-study-section .clinical-study .infobox-title {
    color: #59595b; }
.clinical-study-section .clinical-study .infobox-title h2 {
    font-weight: 700;
    font-size: 1.375rem; }
@media screen and (min-width: 48em) {
    .clinical-study-section .clinical-study .infobox-title h2 {
        font-size: 1.375rem; } }
.clinical-study-section .clinical-study .infobox-title h2 a {
    color: #59595b;
    text-decoration: none; }
.clinical-study-section .clinical-study .infobox-title h2 a:hover {
    color: #f36533; }
.clinical-study-section .clinical-study .infobox-title a {
    color: #59595b; }
.clinical-study-section .clinical-study .infobox-title a h2 {
    font-weight: 700;
    font-size: 1.375rem; }
.clinical-study-section .clinical-study .infobox-title a h2:hover {
    color: #f36533; }
@media screen and (max-width: 75em) {
    .clinical-study-section .clinical-study .infobox-title a h2 {
        font-size: 1.375rem;
        margin-bottom: 0.625rem;
        height: 50px; } }
.clinical-study-section .clinical-study-holder {
    margin-bottom: 2.5rem;
    padding-left: 0;
    padding-right: 0; }
@media screen and (min-width: 62em) {
    .clinical-study-section .clinical-study-holder {
        padding-left: 0.9375rem;
        padding-right: 0.9375rem; } }
.clinical-study-section .clinical-study-holder figure {
    overflow: hidden;
    position: relative;
    margin-bottom: 1.25rem; }
.clinical-study-section .clinical-study-holder figure img {
    -webkit-backface-visibility: hidden;
    backface-visibility: hidden;
    -webkit-transition: -webkit-transform .5s ease-in-out;
    transition: transform .5s ease-in-out;
    -webkit-transform: scale(1);
    -ms-transform: scale(1);
    transform: scale(1); }
.clinical-study-section .clinical-study-holder:hover figure img {
    -webkit-transform: scale(1.1);
    -ms-transform: scale(1.1);
    transform: scale(1.1); }
.clinical-study-section .surveillance-study-holder {
    padding: 0 0 1.75rem 0.3125rem; }
@media screen and (max-width: 35.938em) {
    .clinical-study-section .surveillance-study-holder {
        padding: 0 0 1.75rem 0; } }
.clinical-study-section .clinical-publications-holder {
    padding: 0 0 1.75rem 0.3125rem; }
@media screen and (max-width: 35.938em) {
    .clinical-study-section .clinical-publications-holder {
        padding: 0 0 1.75rem 0; } }
.clinical-study-section .documents-holder {
    padding: 0 0 1.75rem 0.3125rem; }
@media screen and (max-width: 35.938em) {
    .clinical-study-section .documents-holder {
        padding: 0 0 1.75rem 0; } }
@media screen and (max-width: 47.938em) {
    .clinical-study-section img {
        margin: 0 auto;
        display: block;
        width: 100%; } }
@media screen and (max-width: 35.938em) {
    .clinical-study-section img {
        margin: 0 auto;
        display: block; }
    .clinical-study-section h4 {
        text-align: center; } }

.study-section {
    margin: 1.875rem 0 3rem 0; }
.study-section .study-register-section {
    width: 100%;
    display: block;
    color: #544f40;
    font-size: 1.125rem; }
.study-section .study-register-section .highlight-content {
    font-family: georgia;
    font-size: 1.375rem;
    color: #544f40; }
@media screen and (min-width: 48em) {
    .study-section .study-register-section .highlight-content {
        font-size: 1.5rem; } }
.study-section .study-rank-section {
    width: 100%;
    display: block;
    margin: 1.875rem 0 1.875rem 0;
    color: #544f40;
    background: #f0f0f0;
    height: auto; }
.study-section .study-rank-section img {
    display: block;
    margin: 0 auto;
    width: 100%; }
.study-section .study-rank-section span {
    color: #15717d;
    font-weight: 600;
    font-size: 1.25rem;
    text-align: center;
    display: block;
    margin-top: 2.875rem; }
.study-section .study-rank-section .total-rank {
    margin: 0.875rem auto;
    display: block;
    width: 100%;
    text-align: center; }
.study-section .study-rank-section .rank-summary {
    color: #544f40;
    font-size: 1.5rem;
    line-height: 42px; }
.study-section .study-rank-section .available-summaries {
    color: #544f40;
    font-size: 1.25rem; }
.study-section .study-rank-section .summary {
    text-align: center; }
@media screen and (min-width: 48em) {
    .study-section .study-rank-section .summary {
        text-align: left;
        margin-bottom: 3rem; } }
.study-section .study-rank-section .summary b,
.study-section .study-rank-section .summary strong {
    position: relative;
    padding-bottom: 0.25rem; }
.study-section .study-rank-section .summary b:after,
.study-section .study-rank-section .summary strong:after {
    position: absolute;
    content: " ";
    left: 50%;
    margin-left: -0.9375rem;
    bottom: 0;
    border-bottom: 2px solid #15717d;
    width: 1.875rem; }
@media screen and (min-width: 48em) {
    .study-section .study-rank-section .summary b:after,
    .study-section .study-rank-section .summary strong:after {
        left: 0;
        margin-left: 0;
        bottom: 0; } }
.study-section .study-rank-section .summary p {
    margin: 1.25rem 0 1.25rem 0;
    font-size: 1.25rem; }
.study-section .study-rank-section b,
.study-section .study-rank-section strong {
    color: #f36533;
    font-weight: 700;
    font-size: 3.25rem;
    display: block; }
.study-section .alliance-companies-policy-section {
    color: #544f40;
    font-size: 1.125rem; }
.study-section .alliance-companies-policy-section .alliance-companies {
    margin: 0 0 2.25rem; }

.selectric-wrapper {
    position: relative;
    cursor: pointer; }
.selectric-wrapper select option:hover {
    background-color: #f36533; }

.selectric-responsive {
    width: 100%; }

.selectric {
    border: 1px solid #DDD;
    border-radius: 0px;
    background: #FFF;
    position: relative;
    overflow: hidden; }
.selectric .label {
    display: block;
    white-space: nowrap;
    overflow: hidden;
    text-overflow: ellipsis;
    margin: 0 36px 0 10px;
    font-size: 0.875rem;
    line-height: 36px;
    color: #444;
    height: 36px;
    user-select: none; }
.selectric .button {
    display: block;
    position: absolute;
    right: 0;
    top: 0;
    width: 36px;
    height: 36px;
    line-height: 36px;
    background-color: #F8f8f8;
    color: #BBB;
    text-align: center;
    font: 0/0 a;
    *font: 20px/36px Lucida Sans Unicode, Arial Unicode MS, Arial;
    background: url(../img/select-arrow.png) no-repeat center center; }

.selectric-focus .selectric {
    border-color: #aaaaaa; }

.selectric-hover .selectric {
    border-color: #c4c4c4; }
.selectric-hover .selectric .button {
    color: #a2a2a2; }
.selectric-hover .selectric .button:after {
    border-top-color: #a2a2a2; }

.selectric-open {
    z-index: 9999; }
.selectric-open .selectric {
    border-color: #c4c4c4; }
.selectric-open .selectric-items {
    display: block; }

.selectric-disabled {
    filter: alpha(opacity=50);
    opacity: 0.5;
    cursor: default;
    user-select: none; }

.selectric-hide-select {
    position: relative;
    overflow: hidden;
    width: 0;
    height: 0; }
.selectric-hide-select select {
    position: absolute;
    left: -100%; }
.selectric-hide-select.selectric-is-native {
    position: absolute;
    width: 100%;
    height: 100%;
    z-index: 10; }
.selectric-hide-select.selectric-is-native select {
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 100%;
    width: 100%;
    border: none;
    z-index: 1;
    box-sizing: border-box;
    opacity: 0; }

.selectric-input {
    position: absolute !important;
    top: 0 !important;
    left: 0 !important;
    overflow: hidden !important;
    clip: rect(0, 0, 0, 0) !important;
    margin: 0 !important;
    padding: 0 !important;
    width: 1px !important;
    height: 1px !important;
    outline: none !important;
    border: none !important;
    *font: 0/0 a !important;
    background: none !important; }

.selectric-temp-show {
    position: absolute !important;
    visibility: hidden !important;
    display: block !important; }

/* Items box */
.selectric-items {
    display: none;
    position: absolute;
    top: 100%;
    left: 0;
    background: #FFF;
    border: 1px solid #c4c4c4;
    z-index: -1;
    box-shadow: 0 0 10px -6px; }
.selectric-items .selectric-scroll {
    height: 100%;
    overflow: auto; }
.selectric-above .selectric-items {
    top: auto;
    bottom: 100%; }
.selectric-items ul,
.selectric-items li {
    list-style: none;
    padding: 0;
    margin: 0;
    font-size: 0.875rem;
    line-height: 1.25rem;
    min-height: 1.25rem; }
.selectric-items li {
    display: block;
    padding: 10px;
    color: #666;
    cursor: pointer; }
.selectric-items li.selected {
    background: #E0E0E0;
    color: #444; }
.selectric-items li.highlighted {
    background: #f36533;
    color: #FFF; }
.selectric-items li:hover {
    background: #f36533;
    color: #FFF; }
.selectric-items .disabled {
    filter: alpha(opacity=50);
    opacity: 0.5;
    cursor: default !important;
    background: none !important;
    color: #666 !important;
    user-select: none; }
.selectric-items .selectric-group .selectric-group-label {
    font-weight: bold;
    padding-left: 0.625rem;
    cursor: default;
    user-select: none;
    background: none;
    color: #444; }
.selectric-items .selectric-group.disabled li {
    filter: alpha(opacity=100);
    opacity: 1; }
.selectric-items .selectric-group li {
    padding-left: 1.563rem; }

.selectric-form-control-sm .selectric .label {
    line-height: 1.875rem;
    height: 1.875rem;
    font-size: 0.875rem; }
.selectric-form-control-sm .selectric .button {
    height: 1.875rem;
    width: 2.25rem; }
.selectric-form-control-sm .selectric-items li {
    padding-top: 0.25rem;
    padding-bottom: 0.25rem;
    font-size: 0.75rem; }

.SumoSelect p {
    margin: 0; }

.SumoSelect {
    width: 100%;
    /* Filtering style */ }
.SumoSelect p {
    margin: 0; }
.SumoSelect .hidden {
    display: none; }
.SumoSelect .search-txt {
    display: none;
    outline: none; }
.SumoSelect .no-match {
    display: none;
    padding: 0.375rem; }

.SelectBox {
    padding: 0.3125rem 2.5rem 0.3125rem 0.5rem; }

.sumoStopScroll {
    overflow: hidden; }

/* Filtering style */
.SumoSelect.open .search-txt {
    display: inline-block;
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    margin: 0;
    padding: 0.3125rem 0.5rem;
    border: none;
    -webkit-box-sizing: border-box;
    -moz-box-sizing: border-box;
    box-sizing: border-box;
    border-radius: 0.3125rem; }

.SumoSelect.open > .search > span,
.SumoSelect.open > .search > label {
    visibility: hidden; }

/*this is applied on that hidden select. DO NOT USE display:none; or visiblity:hidden; and Do not override any of these properties. */
.SelectClass,
.SumoUnder {
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 100%;
    width: 100%;
    border: none;
    -webkit-box-sizing: border-box;
    -moz-box-sizing: border-box;
    box-sizing: border-box;
    -ms-filter: "progid:DXImageTransform.Microsoft.Alpha(Opacity=0)";
    filter: alpha(opacity=0);
    -moz-opacity: 0;
    -khtml-opacity: 0;
    opacity: 0; }

.SelectClass {
    z-index: 1; }

.SumoSelect > .optWrapper > .options li.opt label,
.SumoSelect > .CaptionCont,
.SumoSelect .select-all > label {
    user-select: none;
    -o-user-select: none;
    -moz-user-select: none;
    -khtml-user-select: none;
    -webkit-user-select: none; }

.SumoSelect {
    display: block;
    position: relative;
    outline: none; }

.SumoSelect:focus > .CaptionCont,
.SumoSelect:hover > .CaptionCont,
.SumoSelect.open > .CaptionCont {
    box-shadow: 0 0 2px #7799D0;
    border-color: #7799D0; }

.SumoSelect > .CaptionCont {
    position: relative;
    border: 1px solid #d5d1ce;
    min-height: 0.875rem;
    background-color: #fff;
    margin: 0; }

.SumoSelect > .CaptionCont > span {
    display: block;
    padding-right: 1.875rem;
    text-overflow: ellipsis;
    white-space: nowrap;
    overflow: hidden;
    cursor: default;
    font-size: 0.875rem; }

/*placeholder style*/
.SumoSelect > .CaptionCont > span.placeholder {
    color: #ccc;
    font-style: italic; }

.SumoSelect > .CaptionCont > label {
    position: absolute;
    top: 0;
    right: 0;
    bottom: 0;
    width: 2.5rem;
    margin: 0; }

.SumoSelect > .CaptionCont > label > i {
    background-image: url("../img/select-arrow.png");
    background-position: center center;
    display: block;
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    margin: auto;
    background-repeat: no-repeat;
    opacity: 0.8; }

.SumoSelect > .optWrapper {
    display: none;
    z-index: 1000;
    top: 1.875rem;
    width: 100%;
    position: absolute;
    left: 0;
    -webkit-box-sizing: border-box;
    -moz-box-sizing: border-box;
    box-sizing: border-box;
    background: #fff;
    border: 1px solid #ddd;
    box-shadow: 2px 3px 3px rgba(0, 0, 0, 0.11);
    border-radius: 3px;
    overflow: hidden; }

.SumoSelect.open > .optWrapper {
    top: 2.188rem;
    display: block; }

.SumoSelect.open > .optWrapper.up {
    top: auto;
    bottom: 100%;
    margin-bottom: 0.3125rem; }

.SumoSelect > .optWrapper ul {
    list-style: none;
    display: block;
    padding: 0;
    margin: 0;
    overflow: auto; }

.SumoSelect > .optWrapper > .options {
    border-radius: 2px;
    position: relative;
    /*Set the height of pop up here (only for desktop mode)*/
    max-height: 250px;
    /*height*/ }

.SumoSelect > .optWrapper.okCancelInMulti > .options {
    border-radius: 2px 2px 0 0; }

.SumoSelect > .optWrapper.selall > .options {
    border-radius: 0 0 2px 2px; }

.SumoSelect > .optWrapper.selall.okCancelInMulti > .options {
    border-radius: 0; }

.SumoSelect > .optWrapper > .options li.group.disabled > label {
    opacity: 0.5; }

.SumoSelect > .optWrapper > .options li ul li.opt {
    padding-left: 1.375rem; }

.SumoSelect > .optWrapper.multiple > .options li ul li.opt {
    padding-left: 3.125rem; }

.SumoSelect > .optWrapper.isFloating > .options {
    max-height: 100%;
    box-shadow: 0 0 100px #595959; }

.SumoSelect > .optWrapper > .options li.opt {
    padding: 0.375rem 0.375rem;
    position: relative;
    border-bottom: 1px solid #f5f5f5; }

.SumoSelect > .optWrapper > .options > li.opt:first-child {
    border-radius: 2px 2px 0 0; }

.SumoSelect > .optWrapper.selall > .options > li.opt:first-child {
    border-radius: 0; }

.SumoSelect > .optWrapper > .options > li.opt:last-child {
    border-radius: 0 0 2px 2px;
    border-bottom: none; }

.SumoSelect > .optWrapper.okCancelInMulti > .options > li.opt:last-child {
    border-radius: 0; }

.SumoSelect > .optWrapper > .options li.opt:hover {
    background-color: #E4E4E4; }

.SumoSelect > .optWrapper > .options li.opt.sel,
.SumoSelect .select-all.sel {
    background-color: #a1c0e4; }

.SumoSelect > .optWrapper > .options li label {
    text-overflow: ellipsis;
    white-space: nowrap;
    overflow: hidden;
    display: block;
    cursor: pointer; }

.SumoSelect > .optWrapper > .options li span {
    display: none; }

.SumoSelect > .optWrapper > .options li.group > label {
    cursor: default;
    padding: 0.5rem 0.375rem;
    font-weight: bold; }

/*Floating styles*/
.SumoSelect > .optWrapper.isFloating {
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    width: 90%;
    bottom: 0;
    margin: auto;
    max-height: 90%; }

/*disabled state*/
.SumoSelect > .optWrapper > .options li.opt.disabled {
    background-color: inherit;
    pointer-events: none; }

.SumoSelect > .optWrapper > .options li.opt.disabled * {
    -ms-filter: "progid:DXImageTransform.Microsoft.Alpha(Opacity=50)";
    /* IE 5-7 */
    filter: alpha(opacity=50);
    /* Netscape */
    -moz-opacity: 0.5;
    /* Safari 1.x */
    -khtml-opacity: 0.5;
    /* Good browsers */
    opacity: 0.5; }

/*styling for multiple select*/
.SumoSelect > .optWrapper.multiple > .options li.opt {
    padding-left: 2.188rem;
    cursor: pointer; }

.SumoSelect > .optWrapper.multiple > .options li.opt span,
.SumoSelect .select-all > span {
    position: absolute;
    display: block;
    width: 1.875rem;
    top: 0;
    bottom: 0;
    margin-left: -35px; }

.SumoSelect > .optWrapper.multiple > .options li.opt span i,
.SumoSelect .select-all > span i {
    position: absolute;
    margin: auto;
    left: 0;
    right: 0;
    top: 0;
    bottom: 0;
    width: 0.875rem;
    height: 0.875rem;
    border: 1px solid #AEAEAE;
    border-radius: 2px;
    box-shadow: inset 0 1px 3px rgba(0, 0, 0, 0.15);
    background-color: #fff; }

.SumoSelect > .optWrapper > .MultiControls {
    display: none;
    border-top: 1px solid #ddd;
    background-color: #fff;
    box-shadow: 0 0 2px rgba(0, 0, 0, 0.13);
    border-radius: 0 0 3px 3px; }

.SumoSelect > .optWrapper.multiple.isFloating > .MultiControls {
    display: block;
    margin-top: 0.3125rem;
    position: absolute;
    bottom: 0;
    width: 100%; }

.SumoSelect > .optWrapper.multiple.okCancelInMulti > .MultiControls {
    display: block; }

.SumoSelect > .optWrapper.multiple.okCancelInMulti > .MultiControls > p {
    padding: 0.375rem; }

.SumoSelect > .optWrapper.multiple.okCancelInMulti > .MultiControls > p:focus {
    box-shadow: 0 0 2px #a1c0e4;
    border-color: #a1c0e4;
    outline: none;
    background-color: #a1c0e4; }

.SumoSelect > .optWrapper.multiple > .MultiControls > p {
    display: inline-block;
    cursor: pointer;
    padding: 0.75rem;
    width: 50%;
    box-sizing: border-box;
    text-align: center; }

.SumoSelect > .optWrapper.multiple > .MultiControls > p:hover {
    background-color: #f1f1f1; }

.SumoSelect > .optWrapper.multiple > .MultiControls > p.btnOk {
    border-right: 1px solid #DBDBDB;
    border-radius: 0 0 0 3px; }

.SumoSelect > .optWrapper.multiple > .MultiControls > p.btnCancel {
    border-radius: 0 0 3px 0; }

/*styling for select on popup mode*/
.SumoSelect > .optWrapper.isFloating > .options li.opt {
    padding: 0.75rem 0.375rem; }

/*styling for only multiple select on popup mode*/
.SumoSelect > .optWrapper.multiple.isFloating > .options li.opt {
    padding-left: 2.188rem; }

.SumoSelect > .optWrapper.multiple.isFloating {
    padding-bottom: 43px; }

.SumoSelect > .optWrapper.multiple > .options li.opt.selected span i,
.SumoSelect .select-all.selected > span i,
.SumoSelect .select-all.partial > span i {
    background-color: #11a911;
    box-shadow: none;
    border-color: transparent;
    background-image: url("data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAgAAAAGCAYAAAD+Bd/7AAAABHNCSVQICAgIfAhkiAAAAAlwSFlzAAALEgAACxIB0t1+/AAAABx0RVh0U29mdHdhcmUAQWRvYmUgRmlyZXdvcmtzIENTNXG14zYAAABMSURBVAiZfc0xDkAAFIPhd2Kr1WRjcAExuIgzGUTIZ/AkImjSofnbNBAfHvzAHjOKNzhiQ42IDFXCDivaaxAJd0xYshT3QqBxqnxeHvhunpu23xnmAAAAAElFTkSuQmCC");
    background-repeat: no-repeat;
    background-position: center center; }

/*disabled state*/
.SumoSelect.disabled {
    opacity: 0.7;
    cursor: not-allowed; }

.SumoSelect.disabled > .CaptionCont {
    border-color: #ccc;
    box-shadow: none; }

/**Select all button**/
.SumoSelect .select-all {
    border-radius: 3px 3px 0 0;
    position: relative;
    border-bottom: 1px solid #ddd;
    background-color: #fff;
    padding: 5rem 0 0.1875rem 2.188rem;
    height: 1.25rem;
    cursor: pointer; }

.SumoSelect .select-all > label,
.SumoSelect .select-all > span i {
    cursor: pointer; }

.SumoSelect .select-all.partial > span i {
    background-color: #ccc; }

/*styling for optgroups*/
.SumoSelect > .optWrapper > .options li.optGroup {
    padding-left: 0.3125rem;
    text-decoration: underline; }

/*  new input */
.selectric-holder {
    margin-bottom: 0.625rem; }
.selectric-holder input {
    border: 0;
    width: 100%;
    padding-right: 2.5rem;
    color: #495057; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .selectric-holder input {
        height: 1.875rem;
        margin-top: 0; } }
@-moz-document url-prefix() {
    .selectric-holder input {
        color: #495057;
        opacity: 1; } }
.selectric-holder .button {
    height: 100%; }

.preclinical-holder {
    margin-top: 1.875rem;
    color: #544f40; }

.table-holder {
    margin-bottom: 1rem; }
.table-holder .table-responsive {
    margin-bottom: 0.625rem; }
.table-holder thead tr {
    background-color: #f36533;
    color: #FFF;
    font-size: 0.75rem; }
@media screen and (min-width: 48em) {
    .table-holder thead tr {
        font-size: 1rem; } }
.table-holder thead tr th {
    cursor: pointer;
    border-color: #f36533;
    padding: 0.3125rem 0.75rem;
    vertical-align: middle; }
.table-holder thead tr th:first-child {
    min-width: 7rem; }
@media screen and (min-width: 62em) {
    .table-holder thead tr th:first-child {
        min-width: 11rem; } }
.table-holder tbody tr td {
    font-size: 0.75rem; }
@media screen and (min-width: 48em) {
    .table-holder tbody tr td {
        font-size: 1rem; } }
.table-holder tbody tr td:first-child {
    color: #15717d;
    text-align: center;
    font-weight: 700;
    vertical-align: middle; }
.table-holder .table-striped tbody tr:nth-of-type(odd) {
    background-color: #FFF; }
.table-holder .table-striped tbody tr:nth-of-type(even) {
    background-color: #f5f5f5; }
@media screen and (min-width: 36em) {
    .table-holder .table-result-info,
    .table-holder .navigation {
        margin-bottom: 0; } }
@media screen and (min-width: 36em) {
    .table-holder .table-result-info .pagination,
    .table-holder .navigation .pagination {
        margin-bottom: 0; } }
.table-holder .page-link {
    color: #544f40; }
.table-holder .page-link span[aria-hidden="true"] {
    display: block;
    width: 0.875rem;
    height: 1.25rem;
    background: url(../img/pagination-arrow.png) no-repeat center center; }
.table-holder .page-link span[aria-hidden="true"]:hover, .table-holder .page-link span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }
.table-holder .page-link:hover {
    color: #FFF;
    text-decoration: none;
    background-color: #f36533;
    border-color: #f36533; }
.table-holder .page-link:hover span[aria-hidden="true"] {
    background-image: url(../img/pagination-arrow-hover.png); }
.table-holder .page-link:hover span[aria-hidden="true"]:hover, .table-holder .page-link:hover span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }

.color-blue {
    color: #15717d; }

.fs-18 {
    font-size: 1.125rem; }

.mainpara-holder {
    font-size: 1.375rem;
    color: #544f40;
    font-family: Georgia, "Times New Roman", Times, serif; }
@media screen and (min-width: 48em) {
    .mainpara-holder {
        font-size: 1.5rem; } }

input,
select,
.form-control {
    border-radius: 0;
    border: 1px solid #ced4da;
    margin-right: 0.25rem; }

.search-holder {
    margin-bottom: 1.25rem; }
.search-holder label {
    font-weight: 700; }

.no-radius {
    border-radius: 0; }

.btn-primary {
    background-color: #f36533;
    border-color: #f36533; }
.btn-primary:hover {
    background-color: #cf4e20;
    border-color: #cf4e20; }
.btn-primary.focus, .btn-primary:focus {
    box-shadow: 0 0 0 0.2rem rgba(243, 101, 51, 0.5); }
.btn-primary:not(:disabled):not(.disabled).active, .btn-primary:not(:disabled):not(.disabled):active {
    background-color: #cf4e20;
    border-color: #cf4e20; }
.btn-primary:not(:disabled):not(.disabled).active:focus, .btn-primary:not(:disabled):not(.disabled):active:focus {
    box-shadow: 0 0 0 0.2rem rgba(243, 101, 51, 0.5);
    box-shadow: none; }

.pager {
    padding-left: 0;
    margin: 0 0;
    list-style: none;
    text-align: center; }
.pager:before, .pager:after {
    content: "";
    display: table; }
.pager:after {
    clear: both; }
.pager li {
    display: inline; }
.pager li > a,
.pager li > span {
    display: inline-block;
    padding: 5px 14px;
    background-color: #FFF;
    border: 1px solid #544f40;
    box-shadow: 0px 0px 3px rgba(0, 0, 0, 0.3);
    color: #f36533; }
.pager li > a i,
.pager li > span i {
    background: url(../img/pagination-arrow-l.png) no-repeat center center;
    height: 14px;
    width: 14px;
    display: block; }
.pager li > a i.fa-chevron-right, .pager li > a i.fa-right,
.pager li > span i.fa-chevron-right,
.pager li > span i.fa-right {
    background: url(../img/pagination-arrow.png) no-repeat center center; }
.pager li > a:hover,
.pager li > a:focus {
    text-decoration: none;
    background-color: #f5f5f5; }
.pager .next > a,
.pager .next > span {
    float: right; }
.pager .previous > a,
.pager .previous > span {
    float: left; }
.pager .disabled > a,
.pager .disabled > a:hover,
.pager .disabled > a:focus,
.pager .disabled > span {
    color: #59595b;
    background-color: #59595b;
    cursor: not-allowed; }

.btn-filter {
    font-size: 0.875rem;
    line-height: 1.125rem;
    font-weight: 700;
    color: #f36533;
    margin-bottom: 0.9375rem;
    padding: 0; }
.btn-filter:hover {
    color: #f36533;
    text-decoration: none; }
.btn-filter i {
    background: url(../img/filter-white.png) no-repeat center center;
    width: 1.25rem;
    height: 1.25rem;
    display: inline-block;
    vertical-align: middle; }

.study-holder {
    margin-bottom: 10px; }
.study-holder .input-group .form-input-field {
    position: relative;
    -ms-flex: 1 1 auto;
    flex: 1 1 auto;
    width: 100%;
    margin-bottom: 0;
    border: 1px solid #ced4da;
    display: block;
    font-size: 1rem;
    line-height: 1.5;
    color: #495057;
    background-color: #fff;
    background-clip: padding-box;
    border: 1px solid #ced4da;
    border-radius: .25rem; }
.study-holder .input-group input {
    display: block;
    line-height: 20;
    line-height: 18px;
    background-clip: padding-box;
    border-radius: .25rem;
    line-height: 18px;
    width: 100%; }
.study-holder .input-group .form-text {
    border: none;
    padding: 0.25rem 0.25rem;
    line-height: 1.5;
    border-radius: .25rem;
    display: block;
    margin-top: 0;
    font-size: 0.875rem; }
@media screen and (max-width: 24em) {
    .study-holder .input-group .form-text {
        padding: 0.25rem 1.25rem 0.25rem 0.25rem; } }
@media screen and (min-width: 24em) {
    .study-holder .input-group .form-text {
        padding: 0.25rem 1.25rem 0.25rem 0.25rem; } }
@media screen and (-ms-high-contrast: active) and (min-width: 24em) {
    .study-holder .input-group .form-text {
        padding: 0.25rem 1.25rem 0.25rem 0.25rem; } }

.advance-search {
    margin: 1.875rem 0 0 0; }
.advance-search .advance-search-section {
    width: 100%;
    display: block;
    color: #544f40; }
.advance-search .search-studies-holder {
    width: 100%;
    display: block;
    color: #544f40; }
.advance-search .text-search-section .text-search span {
    color: #15717d;
    font-weight: 700; }
.advance-search .text-search-section .more-option {
    text-align: left; }
@media screen and (min-width: 62em) {
    .advance-search .text-search-section .more-option {
        text-align: right; } }
.advance-search .text-search-section .more-option a {
    color: #15717d;
    font-weight: 700; }
.advance-search .text-search-section .more-option strong {
    margin-right: 0; }
.advance-search .text-search-section .more-option .text-blue {
    color: #15717d; }
.advance-search .text-search-section .icon-fa {
    width: 1.25rem;
    height: 1.25rem;
    background: url(../img/up-plus.png) no-repeat center center;
    margin-left: 0.3125rem;
    display: inline-block;
    vertical-align: middle;
    margin-left: 0.5rem; }
.advance-search .study-status-section {
    margin-bottom: 2.188rem; }
.advance-search .study-status-section .radio-buttons {
    display: inline; }
@media screen and (max-width: 36em) {
    .advance-search .study-status-section .radio-buttons {
        display: grid; } }
.advance-search .study-status-section .radio-buttons .custom-radio {
    margin-left: 0; }
@media screen and (max-width: 24em) {
    .advance-search .study-status-section .radio-buttons .custom-radio {
        padding: 0 28px; } }
.advance-search .study-status-section .radio-buttons .form-item-trial-status {
    display: block; }
.advance-search .study-status-section .radio-buttons .form-item-trial-status input {
    vertical-align: middle; }
.advance-search .study-status-section .radio-buttons .form-item-trial-status label {
    vertical-align: middle; }

.filter-section {
    margin: 20px 0; }
.filter-section input {
    color: #495057; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-section input {
        color: #495057; } }
.filter-section #filter-section,
.filter-section .filter-section {
    margin-bottom: 1.25rem; }
.filter-section #filter-section .form-text,
.filter-section .filter-section .form-text {
    margin-top: 0;
    display: block; }
.filter-section .first-filter-section {
    margin-bottom: 1.875rem; }
.filter-section .first-filter-section .disease-section input {
    background-color: #FFF;
    font-size: 0.875rem;
    padding: .25rem .5rem;
    line-height: 1.5; }
@media screen and (max-width: 24em) {
    .filter-section .first-filter-section .disease-section input {
        padding: 0.25rem 2.125rem 0.25rem 0.5rem; } }
@media screen and (min-width: 24em) {
    .filter-section .first-filter-section .disease-section input {
        padding: 0.25rem 2.125rem 0.25rem 0.5rem; } }
@media screen and (-ms-high-contrast: active) and (min-width: 24em) {
    .filter-section .first-filter-section .disease-section input {
        padding: 0.25rem 2.125rem 0.25rem 0.5rem; } }

@media screen and (max-width: 61.938em) {
    .filter-section .first-filter-section .country-section label {
        margin: 0.5rem 0 0.5rem 0; } }
.filter-section .first-filter-section .country-section .button {
    height: 100%; }
.filter-section .first-filter-section .postal-code-section input {
    padding: .25rem .5rem;
    font-size: .875rem;
    line-height: 1.5; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-section .first-filter-section .postal-code-section input {
        padding: 0.375rem 0.5rem; } }

@media screen and (max-width: 61.938em) {
    .product-data-section .product-section h3 {
        margin: -0.5rem 0 0.5rem 0; } }
.product-data-section .product-section h3 .label {
    font-size: 0.875rem; }
.product-data-section code {
    color: #646054;
    font-family: Arial, Helvetica, sans-serif;
    font-size: 1rem; }
.product-data-section span {
    color: #495057;
    opacity: 0.9; }
@-moz-document url-prefix() {
    .product-data-section span {
        opacity: 0.7; } }
@media screen and (min-width: 62em) {
    .product-data-section .patient-level-data label {
        margin: 0.5rem 0 0.5rem 0; } }

.postal-code-section .form-control {
    font-size: 0.875rem;
    color: #544f40; }

.custom-control-label .custom-control-input,
.phase-three-section .custom-control-input {
    border: none;
    background: none; }
.custom-control-label .custom-control-input input[type="radio"],
.custom-control-label .custom-control-input input[type="checkbox"],
.phase-three-section .custom-control-input input[type="radio"],
.phase-three-section .custom-control-input input[type="checkbox"] {
    margin-top: 0;
    height: 1.125rem;
    width: 1.125rem; }

.data-holder {
    border-bottom: 1px solid #d5d1ce;
    width: 100%; }

.m-data-holder {
    margin-bottom: 1.25rem; }
.m-data-holder #edit-phase {
    display: -ms-flexbox;
    display: flex;
    -ms-flex-wrap: wrap;
    flex-wrap: wrap;
    margin-right: -15px;
    margin-left: -15px;
    margin-bottom: 1.25rem; }
@media screen and (max-width: 62em) {
    .m-data-holder #edit-phase {
        display: block;
        margin-left: 0; } }
.m-data-holder #edit-phase:before, .m-data-holder #edit-phase:after {
    content: "";
    display: table; }
.m-data-holder #edit-phase:after {
    clear: both; }
@media screen and (min-width: 62em) {
    .m-data-holder #edit-phase .form-type-checkbox {
        position: relative;
        width: 100%;
        min-height: 0.0625rem;
        padding-right: 0.9375rem;
        padding-left: 0.9375rem;
        -ms-flex: 0 0 33.333333%;
        flex: 0 0 33.333333%;
        max-width: 33.333333%; } }

@media screen and (max-width: 35.938em) {
    .filter-button-section button {
        width: 40%; }
    .filter-button-section div {
        justify-content: center; } }
@media screen and (max-width: 48em) {
    .filter-button-section button {
        width: 25%; }
    .filter-button-section button strong {
        font-size: 0.875rem; } }
@media screen and (max-width: 62em) {
    .filter-button-section button {
        width: 24%; } }
@media screen and (max-width: 62em) and (max-width: 35.938em) {
    .filter-button-section button {
        width: 35%; } }

.filter-button-section .filter-buttons {
    justify-content: flex-end; }
.filter-button-section .filter-buttons .filter-search-button {
    display: contents; }
.filter-button-section .filter-buttons .filter-search-button .collaborator {
    justify-content: flex-end; }
.filter-button-section #edit-reset,
.filter-button-section #Keywordsearch {
    color: #FFF; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-button-section #edit-reset #edit-reset, .filter-button-section #edit-reset #Keywordsearch,
    .filter-button-section #Keywordsearch #edit-reset,
    .filter-button-section #Keywordsearch #Keywordsearch {
        color: #FFF; } }

.collaborator .label {
    color: #495057; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .collaborator .label {
        color: #495057; } }

.fs-12 {
    font-size: 0.75rem; }

.fs-13 {
    font-size: 0.8125rem; }

.checklist-list {
    padding: 0;
    margin: 0 0 0.9375rem;
    list-style: none; }
@media screen and (min-width: 62em) {
    .checklist-list {
        margin-bottom: 0; } }
.checklist-list li {
    margin-bottom: 0.25rem;
    color: #544f40; }

.study-type-section {
    margin-bottom: 0.9375rem; }
@media screen and (min-width: 62em) {
    .study-type-section {
        margin-bottom: 0; } }

.search-status .text-search {
    margin-bottom: 0.3125rem; }
@media screen and (min-width: 62em) {
    .search-status .text-search {
        margin-bottom: 0; } }
.search-status .more-option {
    text-align: left; }
@media screen and (min-width: 62em) {
    .search-status .more-option {
        text-align: right; } }
.search-status label {
    margin-bottom: 0; }

#show-panel {
    display: none; }

.text-blue {
    color: #15717d; }

.element-invisible {
    height: 0 !important;
    width: 0 !important;
    margin: 0 !important;
    overflow: hidden !important; }

.study-status-section .search-status strong {
    display: inline-block;
    width: auto; }
@media screen and (max-width: 62em) {
    .study-status-section .search-status strong {
        display: block; } }
.study-status-section .search-status .radio-buttons {
    display: inline-block; }
@media screen and (max-width: 62em) {
    .study-status-section .search-status .radio-buttons {
        display: block;
        width: auto; } }
.study-status-section .search-status .radio-buttons .form-type-radio {
    display: inline-block;
    width: auto;
    padding: 0 0.375rem; }
@media screen and (max-width: 62em) {
    .study-status-section .search-status .radio-buttons .form-type-radio {
        display: block;
        width: auto;
        padding: 0 0.25rem; } }
@media screen and (min-width: 62em) {
    .study-status-section .search-status .radio-buttons .form-type-radio {
        display: inline-block;
        width: auto;
        padding: 0; } }
@-moz-document url-prefix() {
    .study-status-section .search-status .radio-buttons .form-type-radio {
        display: inline-block;
        width: auto;
        padding: 0; } }
.study-status-section .search-status .radio-buttons .form-type-radio .radio-handler {
    position: relative; }
.study-status-section .search-status .radio-buttons .form-type-radio .radio-handler input[type="radio"] + i {
    position: absolute;
    z-index: 2;
    width: 0.875rem;
    height: 0.875rem;
    background: url(../img/radio-empty.png) no-repeat center center;
    right: auto;
    top: 0.3125rem;
    left: -0.0625rem; }
.study-status-section .search-status .radio-buttons .form-type-radio .radio-handler input[type="radio"]:checked + i {
    background: url(../img/radio-fill.png) no-repeat center center; }

.filter-meanu-title i {
    background: url(../img/filter-white.png) no-repeat center center;
    width: 1.25rem;
    height: 1.25rem;
    display: inline-block;
    vertical-align: middle;
    float: right;
    margin: 0.125rem 0; }

.search-studies-holder .input-group .input-group-prepend input {
    border: unset !important; }
.search-studies-holder .input-group .input-group-prepend .btn {
    border: unset !important; }

.studies-holder {
    margin-top: 1.875rem;
    color: #4a4a4a;
    margin-bottom: 1.25rem; }
.studies-holder .topparagraph {
    font-size: 1.375rem;
    font-family: Georgia, "Times New Roman", Times, serif;
    font-weight: 400;
    line-height: 2.125rem;
    color: #4a4a4a; }
@media screen and (min-width: 48em) {
    .studies-holder .topparagraph {
        font-size: 1.5rem; } }
.studies-holder figure {
    padding-right: 0;
    padding-left: 0; }
@media screen and (min-width: 36em) {
    .studies-holder figure {
        padding-right: 0.9375rem;
        padding-left: 0.9375rem; } }

.deep-title {
    color: #15717d; }

.card-parabox-list ul {
    list-style: none;
    padding: 0;
    margin: 0; }
.card-parabox-list ul li {
    margin-bottom: 0.3125rem;
    color: #544f40; }
.card-parabox-list ul li h6 {
    font-weight: 700;
    margin-bottom: 0.25rem; }

@media screen and (min-width: 75em) {
    .infograph-holder {
        margin-top: -3.375rem; } }

.accordion-soar-studies {
    margin-bottom: 0; }
.accordion-soar-studies .card {
    border-radius: 0;
    border-bottom: 1px solid rgba(0, 0, 0, 0.125);
    margin-bottom: 0.75rem; }
.accordion-soar-studies .card:first-of-type {
    border-bottom: 1px solid rgba(0, 0, 0, 0.125); }
.accordion-soar-studies .card:last-of-type {
    margin-bottom: 0; }
.accordion-soar-studies .card .card-header {
    position: relative;
    padding: 0;
    background-color: #FFF;
    border-bottom: 0; }
.accordion-soar-studies .card .card-header h5 {
    position: relative;
    text-align: left;
    font-size: 1.125rem;
    line-height: 1.125rem;
    font-weight: 700;
    vertical-align: top;
    padding: 0; }
.accordion-soar-studies .card .card-header h5 .btn {
    vertical-align: top;
    font-size: 1.125rem;
    line-height: 1.125rem;
    font-weight: 700;
    width: 100%;
    text-align: left;
    padding: 0;
    text-decoration: none;
    color: #544f40;
    padding: 0.875rem 2.188rem 0.875rem 0.9375rem; }
.accordion-soar-studies .card .card-header h5 .btn > span {
    float: none;
    display: block;
    margin-bottom: 0.3125rem; }
@media screen and (min-width: 36em) {
    .accordion-soar-studies .card .card-header h5 .btn > span {
        float: right;
        margin-bottom: 0; } }
.accordion-soar-studies .card .card-header h5 .btn i {
    position: absolute;
    right: 0.625rem;
    top: 50%;
    margin-top: -0.375rem;
    height: 0.75rem;
    width: 0.75rem;
    background: url(../img/plus-icon.png) no-repeat top center; }
.accordion-soar-studies .card .card-header h5 .btn[aria-expanded="true"] {
    color: #f36533; }
.accordion-soar-studies .card .card-header h5 .btn[aria-expanded="true"] i {
    background: url(../img/plus-icon.png) no-repeat 0 bottom; }
.accordion-soar-studies .card .card-header h5 .btn[aria-expanded="true"]:hover i {
    background: url(../img/minus-icon.png) no-repeat 0 bottom; }
.accordion-soar-studies .card .card-header h5 .btn[aria-expanded="true"] i {
    color: #f36533;
    background: url(../img/minus-icon.png) no-repeat 0 bottom; }
.accordion-soar-studies .card .card-header:hover h5 .btn {
    color: #f36533; }
.accordion-soar-studies .card .card-header:hover h5 .btn i {
    background: url(../img/plus-icon.png) no-repeat 0 bottom; }
.accordion-soar-studies .card .card-header:hover h5 i {
    color: #f36533; }
.accordion-soar-studies .card .collapse {
    border-top: 1px solid rgba(0, 0, 0, 0.125); }
.accordion-soar-studies .card .collapse.show {
    background-color: #f5f5f5; }

.card-innerbody .card-parabox {
    margin-bottom: 0.75rem; }
.card-innerbody .card-parabox p {
    margin-bottom: 0; }

.hdd1 {
    font-size: 1.625rem;
    font-weight: 400;
    color: #f36533; }
@media screen and (min-width: 48em) {
    .hdd1 {
        font-size: 2.5rem; } }

.hd2-title {
    font-size: 1.875rem;
    font-weight: 400;
    color: #f36533;
    margin: 0; }

.mainsearch-holder {
    margin-top: 1.875rem; }
.mainsearch-holder .form-item-study-type-filter span {
    color: #495057; }
.mainsearch-holder .form-item-collaborator span {
    color: #495057; }
@-moz-document url-prefix() {
    .mainsearch-holder .form-item-collaborator span {
        color: #495057; } }
@media screen and (max-width: 48em) {
    .mainsearch-holder .no-data {
        margin: 0 1.125rem; } }

.form-searchtrial-holder {
    margin: 0 0 0.9375rem; }
@media screen and (max-width: 47.938em) {
    .form-searchtrial-holder .btn-holder .btn {
        float: right; } }
@media screen and (max-width: 47.938em) {
    .form-searchtrial-holder .btn-holder label {
        display: none !important; } }

.map-holder {
    margin-bottom: 2.5rem;
    box-shadow: 1px 3px 3px rgba(0, 0, 0, 0.25); }

.search-list-holder {
    margin-bottom: 0.9375rem; }
.search-list-holder .search-list-head .search-list-title,
.search-list-holder .search-list-foot .search-list-title {
    font-size: 1rem;
    color: #544f40;
    margin-top: 0.5rem; }

.search-pagination .page-item .page-link.active, .search-pagination .page-item .page-link:hover, .search-pagination .page-item .page-link:focus {
    color: #FFF;
    text-decoration: none;
    background-color: #f36533;
    border-color: #f36533; }
.search-pagination .page-item .page-link {
    color: #544f40;
    padding: 0.3125rem 0.625rem; }
.search-pagination .page-item .page-link span[aria-hidden="true"] {
    display: block;
    width: 0.875rem;
    height: 1.25rem;
    background: url(../img/pagination-arrow.png) no-repeat center center;
    font-size: 0; }
.search-pagination .page-item .page-link span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }
.search-pagination .page-item .page-link[aria-label="Previous"] {
    font-size: 0; }
.search-pagination .page-item .page-link[aria-label="Previous"] span[aria-hidden="true"] {
    display: block;
    width: 0.875rem;
    height: 1.25rem;
    background: url(../img/pagination-arrow-l.png) no-repeat center center;
    font-size: 0; }
.search-pagination .page-item .page-link[aria-label="Previous"] span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link[aria-label="Previous"] span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover-l.png); }
.search-pagination .page-item .page-link:hover, .search-pagination .page-item .page-link:focus {
    color: #FFF;
    text-decoration: none;
    background-color: #f36533;
    border-color: #f36533; }
.search-pagination .page-item .page-link:hover span[aria-hidden="true"], .search-pagination .page-item .page-link:focus span[aria-hidden="true"] {
    background-image: url(../img/pagination-arrow-hover.png); }
.search-pagination .page-item .page-link:hover span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link:hover span[aria-hidden="true"].active, .search-pagination .page-item .page-link:focus span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link:focus span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }
.search-pagination .page-item .page-link:hover[aria-label="Previous"] span[aria-hidden="true"], .search-pagination .page-item .page-link:focus[aria-label="Previous"] span[aria-hidden="true"] {
    background-image: url(../img/pagination-arrow-hover-l.png); }
.search-pagination .page-item .page-link:hover[aria-label="Previous"] span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link:hover[aria-label="Previous"] span[aria-hidden="true"].active, .search-pagination .page-item .page-link:focus[aria-label="Previous"] span[aria-hidden="true"]:hover, .search-pagination .page-item .page-link:focus[aria-label="Previous"] span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover-l.png); }

.search-list-box table {
    width: 100%;
    border-collapse: collapse;
    font-size: 0.75rem;
    line-height: 1.125rem;
    font-weight: 400; }
@media screen and (min-width: 75em) {
    .search-list-box table {
        font-size: 0.875rem; } }
.search-list-box table tr.odd {
    background: #eee; }
@media screen and (max-width: 48em) {
    .search-list-box table tr.odd.odd-mobile {
        background: #FFF; } }
@media screen and (max-width: 62em) {
    .search-list-box table tr.odd.on-mobile {
        background: #FFF; } }
.search-list-box table tr th {
    background: #f36533;
    color: #FFF;
    font-weight: 700;
    font-size: 0.75rem;
    padding: 0.625rem 0.5rem;
    text-align: left;
    border: 0;
    min-height: 1.375rem;
    white-space: nowrap; }
@media screen and (min-width: 75em) {
    .search-list-box table tr th {
        font-size: 1rem; } }
.search-list-box table tr th a {
    color: #FFF;
    text-decoration: none; }
.search-list-box table tr th img {
    height: 0.8125rem;
    width: 0.8125rem; }
.search-list-box table tr th .text-center {
    width: 16%;
    white-space: nowrap; }
.search-list-box table tr td,
.search-list-box table tr th {
    text-align: left;
    border: 0;
    min-height: 1.375rem; }
.search-list-box table tr td {
    padding: 0.9375rem 0.5rem;
    color: #544f40;
    text-align: left;
    border: 0;
    min-height: 1.375rem; }
.search-list-box table tr td.strong-blue {
    color: #15717d; }
.search-list-box table tr td .strong-blue {
    color: #15717d; }
@media screen and (max-width: 62em) {
    .search-list-box table {
        width: 100%;
        display: block; }
    .search-list-box table thead {
        display: block; }
    .search-list-box table thead tr {
        position: absolute;
        top: -9999px;
        left: -9999px; }
    .search-list-box table tbody {
        display: block; }
    .search-list-box table th,
    .search-list-box table td,
    .search-list-box table tr {
        display: block; }
    .search-list-box table tr {
        border: 1px solid #f5f5f5; }
    .search-list-box table tr td {
        border: none;
        border-bottom: 1px solid #f5f5f5;
        position: relative;
        padding-left: 50%;
        text-align: left !important; }
    .search-list-box table tr td:before {
        position: absolute;
        top: 0.375rem;
        left: 0.375rem;
        width: 45%;
        padding-right: 0.625rem;
        white-space: nowrap;
        /* Label the data */
        content: attr(data-column);
        color: #000;
        font-weight: 400;
        text-align: left;
        font-weight: 700; }
    .search-list-box table tr td[colspan="5"] {
        padding-left: 0.5rem;
        text-align: left !important;
        border-bottom: 0; }
    .search-list-box table tr td:nth-child(5) {
        padding-left: 0.5rem;
        text-align: left !important;
        border-bottom: 0; }
    .search-list-box table tr:nth-child(even) {
        border: 0; }
    .search-list-box table tr:nth-child(even) td {
        border: 0; } }
.search-list-box .description-holder {
    padding-right: 1.25rem;
    position: relative;
    margin-bottom: 0.625rem; }
.search-list-box .description-holder .btn-colaps {
    position: absolute;
    right: 0;
    top: 0;
    border-radius: 0;
    border: solid 1px #f36533;
    width: 1rem;
    height: 1rem;
    padding: 0.0625rem 0 0 0.0625rem;
    line-height: 1;
    text-align: center;
    font-size: 0.8125rem;
    color: #f36533; }
.search-list-box .description-holder.show {
    height: auto;
    overflow: visible;
    white-space: normal; }
.search-list-box .description-holder.show .btn-colaps i::before {
    content: "\f068"; }
.search-list-box .description-holder .truncate-wrapper {
    min-height: 1.25rem;
    display: table !important;
    border-collapse: collapse; }
.search-list-box .description-holder .truncate-wrapper .truncate-row {
    display: table-row; }
.search-list-box .description-holder .truncate-wrapper .truncate-row .truncate-cell {
    display: table-cell; }
.search-list-box .description-holder .truncate-wrapper .truncate-row .truncate-cell .truncate-content {
    display: table;
    table-layout: fixed;
    width: 100%; }
.search-list-box .description-holder .truncate-wrapper .truncate-row .truncate-cell .truncate-content .truncate-ellipsis {
    display: table-cell;
    white-space: nowrap;
    text-overflow: ellipsis;
    overflow: hidden; }
.search-list-box .description-holder.show .truncate-wrapper {
    margin-bottom: 0.625rem; }
.search-list-box .description-holder.show .truncate-wrapper .truncate-row .truncate-cell .truncate-content .truncate-ellipsis {
    white-space: normal;
    text-overflow: ellipsis;
    overflow: visible; }

.status-icon {
    width: 2.188rem;
    height: 2.188rem;
    display: block;
    margin: 0 auto 0.3125rem;
    background-image: url(../img/sprite@2x.png);
    background-repeat: no-repeat;
    background-position: 0 0;
    background-size: 2.188rem auto; }
@media screen and (max-width: 62em) {
    .status-icon {
        margin-left: 0; } }
.status-icon.completed {
    background-position: 0 -34px; }
.status-icon.recruiting {
    background-position: 0 -69px; }
.status-icon.not-yet-recruiting {
    background-position: 0 -104px; }
.status-icon.recruitment-complete {
    background-position: 0 -139px; }
.status-icon.on-hold {
    background-position: 0 -174px; }
.status-icon.terminated, .status-icon.withdrawn {
    background-position: 0 -209px; }
.status-icon.status-icon-xl {
    background-image: url(../img/sprite-1-xl.png);
    width: 4.875rem;
    height: 4.875rem;
    background-size: 4.875rem auto; }
@media screen and (max-width: 48em) {
    .status-icon.status-icon-xl {
        margin: 0 auto; } }
.status-icon.status-icon-xl.completed {
    background-position: 0 -78px; }
.status-icon.status-icon-xl.recruiting {
    background-position: 0 -156px; }
.status-icon.status-icon-xl.not-yet-recruiting {
    background-position: 0 -234px; }
.status-icon.status-icon-xl.recruitment-complete {
    background-position: 0 -314px; }
.status-icon.status-icon-xl.on-hold {
    background-position: 0 -391px; }
.status-icon.status-icon-xl.terminated, .status-icon.status-icon-xl.withdrawn {
    background-position: 0 -471px; }

.age-bar-icon {
    background-image: url(../img/icon-age-bar.png);
    background-repeat: no-repeat;
    background-position: 0 0;
    padding-left: 3rem;
    height: 2.875rem;
    font-size: 1.5rem;
    color: #544f40;
    line-height: 2.875rem;
    min-width: 7.875rem;
    font-weight: 700; }
.age-bar-icon.age-bar-icon-female {
    background-image: url(../img/icon-age-bar-female.png); }
.age-bar-icon.age-bar-icon-male {
    background-image: url(../img/icon-age-bar-male.png); }
@media screen and (max-width: 48em) {
    .age-bar-icon {
        height: 2.125rem;
        line-height: 2.125rem;
        font-size: 1.25rem;
        background-size: 2.125rem auto; } }

.strong-blue {
    color: #15717d;
    font-weight: 700; }

.gsk-lny {
    min-width: 8.5rem;
    white-space: nowrap; }

.visible-mobile {
    display: none !important; }
@media screen and (max-width: 47.938em) {
    .visible-mobile {
        display: inline !important; } }

.visible-mobile-block {
    display: none !important; }
@media screen and (max-width: 47.938em) {
    .visible-mobile-block {
        display: block !important; } }

.visible-mobile-max-block {
    display: none !important; }
@media screen and (max-width: 62em) {
    .visible-mobile-max-block {
        display: block !important; } }

.visible-tablet-up {
    display: inline !important; }
@media screen and (max-width: 47.938em) {
    .visible-tablet-up {
        display: none !important; } }

.visible-tablet-up-block {
    display: block !important; }
@media screen and (max-width: 47.938em) {
    .visible-tablet-up-block {
        display: none !important; } }

.visible-tablet-max-block {
    display: block !important; }
@media screen and (max-width: 62em) {
    .visible-tablet-max-block {
        display: none !important; } }

.search-list-foot li a .fa-chevron-right:before,
.search-list-foot li a .fa-chevron-left:before,
.search-list-head li a .fa-chevron-right:before,
.search-list-head li a .fa-chevron-left:before {
    display: none;
    content: ""; }

.filter-menu-holder {
    background-color: #f5f5f5;
    padding: 0 0.5625rem 2.5rem;
    margin-bottom: 0.9375rem; }
.filter-menu-holder .filter-info {
    color: #15717d;
    margin-bottom: 0.625rem;
    line-height: 1.125rem; }
@media screen and (min-width: 62em) {
    .filter-menu-holder.collapse:not(.show) {
        display: block; } }
.filter-menu-holder .reset-btn {
    width: 88px;
    margin: 0px 12px;
    font-size: .875rem; }
@media screen and (max-width: 1024px) and (orientation: landscape) {
    .filter-menu-holder .reset-btn {
        margin: 0 0; } }
.filter-menu-holder .search-btn {
    margin: 0 12px;
    font-size: .875rem; }
@media screen and (max-width: 1024px) and (orientation: landscape) {
    .filter-menu-holder .search-btn {
        float: right;
        margin: 0 0; } }
.filter-menu-holder .filter-accordion {
    margin-top: 10px; }

.filterbutton-holder {
    float: right; }

.filter-meanu-title {
    background-color: #f36533;
    height: 2.125rem;
    position: relative;
    font-weight: 400;
    color: #FFF;
    padding: 0.3125rem 0.625rem;
    font-size: 1rem;
    margin-bottom: 0.625rem;
    margin-left: -0.5625rem;
    margin-right: -0.5625rem;
    display: none; }
@media screen and (min-width: 48em) {
    .filter-meanu-title {
        display: block; } }
.filter-meanu-title .btn-reset {
    font-size: 0.875rem;
    position: absolute;
    right: 0;
    top: 0;
    bottom: 0;
    background-color: #f36533;
    padding: 0.3125rem 0.3125rem;
    color: #FFF;
    text-decoration: underline; }
.filter-meanu-title .btn-reset input {
    text-decoration: none;
    background-color: #f36533;
    border: 0;
    color: #FFF;
    cursor: pointer; }
.filter-meanu-title .filter-icon {
    margin-left: 0.3125rem; }
.filter-meanu-title .btn-reset-mobile {
    font-size: 0.875rem;
    position: absolute;
    right: 75px;
    top: 0;
    bottom: 0;
    padding: 0.875rem 0.9375rem;
    color: #FFF;
    text-decoration: underline; }
@media screen and (max-width: 47.938em) {
    .filter-meanu-title.filter-meanu-title-mobile {
        display: block; } }
.filter-meanu-title.filter-meanu-title-mobile .btn-filter {
    margin: 2px 0;
    float: right; }

.menu-filter .menu-section {
    border-bottom: solid 1px #544f40;
    margin-bottom: 0.3125rem; }
.menu-filter .menu-section > .menu-title {
    font-size: 1rem;
    color: #544f40;
    margin-right: 1.5rem;
    padding-left: 1.625rem;
    margin-bottom: 0.9375rem;
    display: block;
    position: relative;
    text-decoration: none; }
.menu-filter .menu-section > .menu-title a {
    font-size: 1rem;
    color: #d5d1ce;
    position: relative;
    text-decoration: none; }
.menu-filter .menu-section ul {
    list-style: none;
    padding: 0;
    margin: 0; }

.backdrop-hide .modal-backdrop {
    display: none; }
.backdrop-hide .modal-backdrop.show {
    display: none; }

.fs12 {
    font-size: 0.75rem; }

.filter-select-holder {
    margin-bottom: 0.625rem; }
.filter-select-holder label {
    display: block;
    margin: 0;
    font-weight: 700;
    color: #544f40; }
.filter-select-holder .label {
    opacity: 0.9; }
.filter-select-holder .form-item-pcode-filter input {
    color: #495057; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-select-holder .form-item-pcode-filter input {
        height: 1.875rem; } }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-select-holder .form-item-keyword-filter input {
        height: 1.875rem;
        color: #495057; } }
@-moz-document url-prefix() {
    .filter-select-holder .form-item-keyword-filter input {
        color: #495057; } }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .filter-select-holder .form-item-keyword-filter input {
        padding: 0.25rem 0.625rem; } }

.filter-accordion {
    margin-top: 0.3125rem;
    margin-bottom: 1.25rem; }
.filter-accordion .collapse-container > :nth-child(odd) {
    margin-top: 0; }
.filter-accordion .collapse-container > :nth-child(even) {
    margin-top: 0; }
.filter-accordion .collapse-container > :nth-child(odd):hover {
    cursor: pointer;
    -moz-user-select: none;
    /* mozilla browsers */
    -khtml-user-select: none;
    /* webkit browsers */ }
.filter-accordion .gsk-menu-title {
    color: #544f40;
    font-weight: 700;
    position: relative;
    margin: 0 0 0.5rem;
    padding-right: 1.563rem; }
.filter-accordion .gsk-menu-collapsible {
    font-size: 0.875rem;
    color: #544f40; }
.filter-accordion .gsk-menu-collapsible ul {
    padding: 0;
    margin: 0;
    list-style: none; }
.filter-accordion .gsk-menu-collapsible ul li {
    position: relative;
    padding: 0;
    font-size: 0.8125rem;
    margin-bottom: 0.625rem; }
.filter-accordion .gsk-menu-collapsible ul li .checkbox-handler {
    padding-left: 1.25rem;
    display: inline-block;
    top: auto;
    right: auto;
    cursor: pointer; }
.filter-accordion .arrow-r {
    width: 12px;
    height: 12px;
    background: url(../img/icon-minus.jpg) no-repeat center center;
    position: absolute;
    right: 0.3125rem;
    top: 50%;
    margin-top: -0.3125rem; }
.filter-accordion .arrow-d {
    width: 12px;
    height: 12px;
    background: url(../img/icon-plus.jpg) no-repeat center center;
    position: absolute;
    right: 0.3125rem;
    top: 50%;
    margin-top: -0.3125rem; }

.search-status .form-item-trial-status #edit-trial-status .radio-handler {
    padding: 0 1rem; }
@supports (-ms-ime-align: auto) {
    .search-status .form-item-trial-status #edit-trial-status .radio-handler {
        padding: 0 1rem; } }

.checkbox-handler,
.radio-handler {
    padding: 0 1.125rem;
    position: relative; }
.checkbox-handler input[type="checkbox"] + i,
.checkbox-handler input[type="radio"] + i,
.radio-handler input[type="checkbox"] + i,
.radio-handler input[type="radio"] + i {
    position: absolute;
    z-index: 2;
    width: 0.875rem;
    height: 0.875rem;
    background: url(../img/checkbox-empty.png) no-repeat center center;
    right: auto;
    top: 0.1875rem;
    left: 0; }
.checkbox-handler input[type="radio"] + i,
.radio-handler input[type="radio"] + i {
    background: url(../img/radio-empty.png) no-repeat center center; }
.checkbox-handler input[type="checkbox"]:checked + i,
.radio-handler input[type="checkbox"]:checked + i {
    background: url(../img/checkbox-fill.png) no-repeat center center; }
.checkbox-handler input[type="radio"]:checked + i,
.radio-handler input[type="radio"]:checked + i {
    background: url(../img/radio-fill.png) no-repeat center center; }
@supports (-ms-ime-align: auto) {
    .checkbox-handler .form-radio,
    .radio-handler .form-radio {
        display: none; } }

.checkbox-handler input[type=checkbox],
.checkbox-handler input[type=radio],
.radio-handler input[type=checkbox],
.radio-handler input[type=radio] {
    margin-right: 0.3125rem;
    display: none; }

.menu-filter .checkbox-handler input[type="checkbox"] + i,
.menu-filter .checkbox-handler input[type="radio"] + i,
.menu-filter .radio-handler input[type="checkbox"] + i,
.menu-filter .radio-handler input[type="radio"] + i {
    top: 0.0625rem;
    left: -0.0625rem; }

.menu-filter .gsk-menu-collapsible ul li .checkbox-handler {
    padding-left: 0; }
.menu-filter .gsk-menu-collapsible ul li .checkbox-handler input[type="checkbox"] + i {
    top: 0; }

.filter-select-holder #edit-patient-level-sharing-filter label {
    position: relative;
    font-weight: 600;
    color: #544f40;
    font-size: 0.875rem; }
.filter-select-holder #edit-patient-level-sharing-filter label span {
    position: absolute;
    display: block;
    top: 0;
    right: 0;
    left: 1.125rem; }
.filter-select-holder #edit-vaccines-filter label {
    font-size: 0.75rem; }

.custom-control .custom-control-label:before {
    width: 1rem;
    height: 1rem;
    pointer-events: none;
    content: "";
    -webkit-user-select: none;
    -moz-user-select: none;
    -ms-user-select: none;
    user-select: none;
    background-color: transparent;
    border: solid 1px #a2a2a2; }

.custom-radio .custom-control-input:checked ~ .custom-control-label::before {
    background-color: #f36533; }

.btn-back {
    background: url(../img/icon-angle-left.png) no-repeat left center;
    padding-left: 0.9375rem;
    border-radius: 0;
    color: #4a4a4a; }
.btn-back:hover {
    color: #f36533; }
.btn-back:active {
    background: url(../img/icon-angle-left.png) no-repeat left center !important; }

.studydetail-holder {
    font-family: Arial, Helvetica, sans-serif; }
.studydetail-holder .study-info-holder .study-info-right {
    width: 8.625rem;
    height: 8.625rem;
    background-color: #f36533;
    text-align: center;
    display: block;
    margin: 0 auto 0.9375rem; }
@media screen and (min-width: 62em) {
    .studydetail-holder .study-info-holder .study-info-right {
        float: right; } }
.studydetail-holder .study-info-holder .study-info-left {
    font-family: Arial, Helvetica, sans-serif;
    font-size: 1.375rem;
    color: #544f40;
    line-height: 2.125rem;
    margin-bottom: 1.25rem; }
@media screen and (min-width: 62em) {
    .studydetail-holder .study-info-holder .study-info-left {
        margin-right: 10.63rem; } }
@media screen and (min-width: 48em) {
    .studydetail-holder .study-info-holder .study-info-left {
        font-size: 1.125rem; } }
.studydetail-holder .status-icon-holder {
    height: 100%;
    width: 100%;
    display: flex;
    align-items: center;
    justify-content: center; }
.studydetail-holder .status-icon-holder .status-icon-center {
    color: #FFF;
    font-size: 1.125rem; }
.studydetail-holder .status-icon-holder .status-icon-center p {
    margin: 0; }

.status-white-icon {
    width: 2.875rem;
    height: 2.875rem;
    display: block;
    margin: 0 auto 0.3125rem;
    background-image: url(../img/sprite-white@2x.png);
    background-repeat: no-repeat;
    background-position: 0 0;
    background-size: 2.875rem auto; }
.status-white-icon.completed {
    background-position: 0px -44px; }
.status-white-icon.recruiting {
    background-position: 0px -91px; }
.status-white-icon.not-yet-recruiting {
    background-position: 0 -137px; }
.status-white-icon.recruitment-complete {
    background-position: 0 -182px; }
.status-white-icon.on-hold {
    background-position: 0 -228px; }
.status-white-icon.terminated, .status-white-icon.withdrawn {
    background-position: 0 -274px; }

.studyinfo-detail-holder {
    margin: 0; }
.studyinfo-detail-holder .dbl-hr {
    display: none; }
@media screen and (min-width: 36em) {
    .studyinfo-detail-holder .dbl-hr {
        display: block; } }
.studyinfo-detail-holder .gskstudy-top a {
    text-decoration: underline; }
@media screen and (min-width: 62em) {
    .studyinfo-detail-holder .gskstudy-top a:after {
        border-bottom: solid 0.125rem #d5d1ce;
        width: 120px;
        margin: 0 auto; } }
@media screen and (max-width: 62em) {
    .studyinfo-detail-holder .gskstudy-top a:after {
        border-bottom: solid 0.125rem #d5d1ce;
        width: 120px;
        margin: 0 auto; } }

.gskstudy-grid-holder .gskstudy-grid {
    position: relative;
    text-align: left;
    color: #544f40;
    padding-top: 0.3125rem;
    width: 100%;
    margin-bottom: 1.25rem;
    padding-left: 5.875rem; }
@media screen and (min-width: 36em) {
    .gskstudy-grid-holder .gskstudy-grid {
        height: 100%;
        margin-bottom: 0;
        padding-left: 0;
        text-align: center; } }
.gskstudy-grid-holder .gskstudy-grid:after {
    position: relative;
    right: 0;
    top: 0;
    bottom: 0;
    width: 0.125rem; }
@media screen and (min-width: 36em) {
    .gskstudy-grid-holder .gskstudy-grid:after {
        content: " ";
        right: 0;
        border-right: solid 0.125rem #d5d1ce;
        position: absolute; } }
.gskstudy-grid-holder .gskstudy-grid .stdview-icon {
    margin-bottom: 0.9375rem; }
.gskstudy-grid-holder .gskstudy-grid h6 {
    color: #15717d;
    font-weight: 400;
    font-size: 1.125rem;
    margin-bottom: 0.3125rem; }
@media screen and (min-width: 48em) {
    .gskstudy-grid-holder .gskstudy-grid h6 {
        font-size: 0.875rem; } }
@media screen and (min-width: 62em) {
    .gskstudy-grid-holder .gskstudy-grid h6 {
        font-size: 1.125rem; } }
.gskstudy-grid-holder .gskstudy-grid p {
    margin: 0;
    font-size: 1.125rem; }
@media screen and (min-width: 48em) {
    .gskstudy-grid-holder .gskstudy-grid p {
        font-size: 0.875rem; } }
@media screen and (min-width: 62em) {
    .gskstudy-grid-holder .gskstudy-grid p {
        font-size: 1rem; } }
.gskstudy-grid-holder .gskstudy-grid a {
    color: #544f40; }
.gskstudy-grid-holder .gskstudy-grid .stdview-icon {
    display: block;
    position: absolute;
    left: 0.9375rem;
    top: 50%;
    margin-top: -25px;
    margin-bottom: 0; }
@media screen and (min-width: 36em) {
    .gskstudy-grid-holder .gskstudy-grid .stdview-icon {
        position: static;
        left: auto;
        top: auto;
        margin-top: 0;
        margin-bottom: 0.9375rem; } }
.gskstudy-grid-holder .gskstudy-grid.gskstudy-top {
    position: static;
    text-align: center;
    padding-left: 0; }
.gskstudy-grid-holder .gskstudy-grid.gskstudy-top strong i {
    color: #f36533;
    margin: 0 4px; }
.gskstudy-grid-holder div[class*='gsk-col']:last-child .gskstudy-grid:after {
    border-right: 0; }

.dbl-hr {
    border-top: solid 0.125rem #d5d1ce;
    margin-top: 0.9375rem;
    margin-bottom: 0.9375rem; }

.stdoverview-holder {
    margin-top: 1.875rem;
    margin-bottom: 1.875rem; }
.stdoverview-holder h2 {
    font-weight: 400;
    font-size: 1.875rem;
    color: #f36533;
    margin-bottom: 2.5rem; }

.stdview-icon {
    height: 3.125rem;
    display: block;
    margin: 0 auto;
    background-image: url(../img/sprite2@2x.png);
    background-repeat: no-repeat;
    background-position: 0 0;
    background-size: 3.125rem auto;
    width: 3.125rem; }
.stdview-icon.condition {
    background-position: 0 -448px; }
.stdview-icon.products {
    background-position: 0 -398px; }
.stdview-icon.collaborator {
    background-position: 0 -349px; }
.stdview-icon.date {
    background-position: 0 -298px; }
.stdview-icon.type {
    background-position: 0 -248px; }
.stdview-icon.phase {
    background-position: 0 -198px; }
.stdview-icon.gender {
    background-position: 0 -148px; }
.stdview-icon.age {
    background-position: 0 -99px; }
.stdview-icon.volunteers {
    background-position: 0 -48px; }

.location-holder {
    margin-bottom: 1.625rem; }
.location-holder .location-title {
    font-size: 1.875rem;
    color: #f36533;
    margin-bottom: 1.25rem; }
.location-holder .contact-details-section {
    margin-bottom: 0.9375rem; }
@media screen and (max-width: 48em) {
    .location-holder .contact-details-section {
        margin: 0 auto;
        width: 100%;
        display: block; } }
.location-holder .contact-details-section ul {
    list-style: none;
    padding: 0;
    margin: 0 0 1.25rem; }
.location-holder .contact-details-section ul li {
    margin: 0 0 0.25rem;
    color: #544f40; }
.location-holder .contact-details-section ul li h6 {
    font-weight: 700;
    margin: 0 0 0.1875rem; }
.location-holder .contact-details-section ul li p {
    margin: 0; }
@media screen and (max-width: 62em) {
    .location-holder .contact-details-section ul li p {
        font-size: 0.875rem; } }
.location-holder .contact-details-section ul li span,
.location-holder .contact-details-section ul li a {
    color: #544f40; }
.location-holder .contact-details-section ul li span:hover,
.location-holder .contact-details-section ul li a:hover {
    text-decoration: underline; }
.location-holder .contact-details-section.details-section-scroller {
    height: 13.75rem;
    overflow-y: scroll;
    min-height: 7.5rem;
    margin-bottom: 1.5rem;
    border: solid 1px #d5d1ce; }
@media screen and (min-width: 62em) {
    .location-holder .contact-details-section.details-section-scroller {
        height: 21.63rem; } }
@media screen and (min-width: 75em) {
    .location-holder .contact-details-section.details-section-scroller {
        height: 25.63rem;
        position: absolute;
        top: 0;
        bottom: 0;
        left: 0;
        overflow-y: scroll;
        min-height: 7.5rem;
        margin-bottom: 1.5rem;
        border: solid 1px #d5d1ce; } }
.location-holder .contact-details-section.details-section-scroller .country-data {
    min-height: 7.5rem;
    margin-bottom: 0; }
.location-holder .contact-details-section.details-section-scroller .country-data table {
    margin-bottom: 0; }
.location-holder .country-data {
    margin-bottom: 1.563rem; }
.location-holder .country-data table {
    border-top: 2px solid #f36533; }
.location-holder .country-data table tbody tr td {
    padding-left: 0.625rem;
    padding-right: 0.625rem;
    color: #544f40;
    line-height: 1.125rem; }
.location-holder .country-data table tbody tr:nth-child(odd) {
    background-color: #f5f5f5; }
.location-holder .map-border-box {
    border: solid 2px #dbdbdb;
    margin-bottom: 1.563rem; }

.see-more {
    font-weight: 700;
    color: #f36533; }
.see-more:hover {
    color: #15717d; }

.gsk-sdtdesign-holder h2 {
    font-size: 1.875rem;
    color: #f36533;
    margin-bottom: 1.25rem; }
.gsk-sdtdesign-holder .gsk-stddesign-list {
    color: #544f40;
    margin-bottom: 1.875rem; }
.gsk-sdtdesign-holder .gsk-stddesign-list ul {
    list-style: none;
    padding: 0;
    margin: 0; }
.gsk-sdtdesign-holder .gsk-stddesign-list ul li {
    margin-bottom: 0.75rem; }
.gsk-sdtdesign-holder .gsk-stddesign-list ul li strong {
    display: inline-block;
    min-width: 13.75rem;
    vertical-align: middle; }
@media screen and (max-width: 36em) {
    .gsk-sdtdesign-holder .gsk-stddesign-list ul li strong {
        min-width: 10.38rem; } }
@media screen and (max-width: 24em) {
    .gsk-sdtdesign-holder .gsk-stddesign-list ul li strong {
        min-width: 9.625rem; } }
.gsk-sdtdesign-holder .gsk-stddesign-list ul li span {
    display: inline-block;
    vertical-align: middle;
    text-transform: capitalize; }
.gsk-sdtdesign-holder .outcome-holder {
    margin-bottom: 0.9375rem; }
.gsk-sdtdesign-holder .outcome-holder .outcome-box {
    color: #544f40;
    padding-left: 0.75rem;
    font-size: 1rem; }
.gsk-sdtdesign-holder .outcome-holder .outcome-box h5 {
    font-weight: 700;
    margin-left: -0.75rem;
    font-size: 1rem; }
.gsk-sdtdesign-holder .outcome-holder .outcome-box h6 {
    font-size: 1rem;
    font-weight: 700;
    margin-left: -0.75rem;
    padding-left: 0.5rem;
    margin-bottom: 0.1875rem; }
.gsk-sdtdesign-holder .outcome-holder .outcome-box i {
    margin-left: 1.375rem;
    font-size: 0.3125rem; }
@media screen and (max-width: 64em) {
    .gsk-sdtdesign-holder .outcome-holder .outcome-box i {
        font-size: 0.375rem; } }
.gsk-sdtdesign-holder .outcome-holder .outcome-box p {
    font-weight: 700;
    padding-left: 0.5rem;
    margin-bottom: 0;
    display: inline-block; }

.interventions-holder {
    margin-bottom: 1.25rem; }
.interventions-holder .interventions-box {
    color: #544f40;
    padding-left: 0.75rem;
    font-size: 1rem;
    margin-bottom: 0.625rem; }
.interventions-holder .interventions-box h4 {
    font-size: 1.125rem;
    color: #544f40;
    margin-bottom: 0.9375rem;
    font-weight: 700; }
.interventions-holder .interventions-box i {
    margin-left: 1.375rem;
    font-size: 5px; }
@media screen and (max-width: 64em) {
    .interventions-holder .interventions-box i {
        font-size: 0.375rem; } }
.interventions-holder .interventions-box h5 {
    font-size: 1rem;
    font-weight: 700;
    padding-left: 0.5rem;
    margin-bottom: 0.1875rem;
    display: inline-block; }
.interventions-holder .interventions-box h5 span {
    font-weight: 400; }
.interventions-holder .interventions-box h5 a {
    color: #f36533; }
.interventions-holder .interventions-box i {
    margin-left: 1.375rem;
    font-size: 0.3125rem; }
@media screen and (max-width: 64em) {
    .interventions-holder .interventions-box i {
        font-size: 0.375rem; } }
.interventions-holder .interventions-box p {
    font-weight: 700;
    margin-left: 0;
    padding-left: 0.5rem;
    margin-bottom: 0;
    display: inline-block; }

.stdocument-holder {
    margin-bottom: 1.125rem; }
.stdocument-holder h2 {
    font-size: 1.875rem;
    color: #f36533;
    margin-bottom: 1.25rem;
    font-weight: 400; }

.tooltip-inner {
    background-color: #ffffff !important;
    color: #000000 !important;
    border: 1px solid #544f40;
    opacity: 1;
    padding: 0.1875rem 0.5rem; }

.tooltip.top .tooltip-arrow {
    border-top-color: #ffffff; }
.tooltip.top .tooltip-arrow:before {
    border-bottom-color: #ffffff; }

.tooltip.right .tooltip-arrow {
    border-right-color: #ffffff !important; }

.tooltip.bottom .tooltip-arrow {
    border-bottom-color: #ffffff !important; }

.tooltip.left .tooltip-arrow {
    border-left-color: #ffffff !important; }
.tooltip.left .tooltip-arrow:before {
    border-bottom-color: #ffffff; }

.common-modal {
    padding: 0; }
@media screen and (min-width: 75em) {
    .common-modal .modal-xl {
        max-width: 1170px; } }
.common-modal .modal-xlg {
    max-width: 920px; }
.common-modal .modal-content {
    border-radius: 0; }
.common-modal .modal-content .close-btn {
    background-color: #f36533;
    padding: 0.625rem;
    height: 2.75rem;
    width: 2.75rem;
    text-align: center;
    opacity: 1;
    z-index: 1;
    position: relative; }
.common-modal .modal-content .close-btn img {
    display: block; }
.common-modal .modal-content .modal-title h5 {
    text-align: center; }
.common-modal .modal-content .medical-condition-detail {
    margin: 10px 0; }
.common-modal .modal-content .medical-condition-detail .condition-holder {
    margin-bottom: 0.9375rem; }
.common-modal .modal-content .medical-condition-detail .condition-holder h6 {
    font-size: 1.125rem;
    color: #f36533;
    font-weight: 700;
    margin-bottom: 0.125rem;
    margin: 0 0 0.3125rem;
    border-bottom: solid 1px #f36533;
    font-size: 1rem;
    padding-bottom: 0.3125rem; }
.common-modal .modal-content .medical-condition-detail .condition-holder h6 a {
    font-size: 1.125rem;
    color: #f36533;
    font-weight: 700; }
.common-modal .modal-content .medical-condition-detail .condition-holder h6 a:hover, .common-modal .modal-content .medical-condition-detail .condition-holder h6 a.active {
    color: #FFF;
    background-color: #f36533; }
.common-modal .modal-content .medical-condition-detail .condition-holder ul {
    list-style: none;
    padding: 0;
    margin: 0;
    line-height: 1.125rem; }
.common-modal .modal-content .medical-condition-detail .condition-holder ul li {
    display: inline-block;
    vertical-align: top; }
.common-modal .modal-content .medical-condition-detail .condition-holder ul li a {
    color: #544f40;
    position: relative;
    padding: 0 0.1875rem 0 0.1875rem;
    font-size: 0.875rem; }
.common-modal .modal-content .medical-condition-detail .condition-holder ul li a:hover, .common-modal .modal-content .medical-condition-detail .condition-holder ul li a.active {
    color: #FFF;
    background-color: #f36533; }
.common-modal .modal-content .medical-condition-detail .condition-holder ul li a strong {
    text-decoration: none; }
.common-modal .modal-content .location-details {
    padding-left: 0.9375rem;
    padding-right: 0.9375rem; }
.common-modal .modal-content .location-details .location-holder {
    margin-bottom: 0.9375rem; }
.common-modal .modal-content .location-details .location-holder h6 {
    font-size: 1.125rem;
    color: #f36533;
    font-weight: 700;
    margin-bottom: 0.125rem;
    border-bottom: solid 1px #f36533;
    padding-bottom: 0.3125rem;
    cursor: pointer; }
.common-modal .modal-content .location-details .location-holder ul {
    list-style: none;
    padding: 0;
    margin: 0;
    line-height: 1.125rem; }
.common-modal .modal-content .location-details .location-holder ul li {
    display: inline-block;
    vertical-align: top; }
.common-modal .modal-content .location-details .location-holder ul li a {
    color: #544f40;
    position: relative;
    padding: 0 0.1875rem 0 0.1875rem;
    font-size: 0.875rem; }
.common-modal .modal-content .location-details .location-holder ul li a:hover, .common-modal .modal-content .location-details .location-holder ul li a.active {
    color: #FFF;
    background-color: #f36533; }
.common-modal .modal-content .location-details .location-holder ul li a strong {
    text-decoration: none; }
.common-modal .modal-content .product-details p {
    padding: 0 1.25rem;
    background-color: #f5f5f5; }
.common-modal .modal-content .product-details .search-field {
    margin: 1.688rem 0;
    width: 100%; }
.common-modal .modal-content .product-details .search-field .input-group {
    float: right; }
.common-modal .modal-content .product-details .search-field .input-group-prepend {
    display: inline-block; }
.common-modal .modal-content .product-details .search-field .input-group-prepend h6 {
    font-size: 1rem;
    color: #f36533;
    font-weight: 700; }
.common-modal .modal-content .product-details .search-field .input-group-prepend h6 a {
    font-size: 1.125rem;
    color: #f36533;
    font-weight: 700; }
.common-modal .modal-content .product-details .search-field .input-group-prepend h6 a:hover, .common-modal .modal-content .product-details .search-field .input-group-prepend h6 a:focus {
    color: #FFF;
    background-color: #f36533; }
.common-modal .modal-content .product-details .alphabetical-pagination {
    margin: 0 auto; }
.common-modal .modal-content .product-details .alphabetical-pagination ul {
    margin: 0 0 0.625rem;
    list-style-type: none; }
.common-modal .modal-content .product-details .alphabetical-pagination .pagination {
    padding: 0;
    width: 100%; }
.common-modal .modal-content .product-details .alphabetical-pagination .page-link {
    padding: 0 0.125rem;
    border: none;
    background: none;
    color: #544f40;
    font-weight: 700; }
.common-modal .modal-content .product-details .alphabetical-pagination .page-link:hover, .common-modal .modal-content .product-details .alphabetical-pagination .page-link.active {
    color: #f36533; }
@media screen and (max-width: 24em) {
    .common-modal .modal-content .product-details .alphabetical-pagination .page-link {
        padding: 0 1px; } }
@media screen and (min-width: 24em) {
    .common-modal .modal-content .product-details .alphabetical-pagination .page-link {
        padding: 0 2px; } }
@media screen and (min-width: 48em) {
    .common-modal .modal-content .product-details .alphabetical-pagination .page-link {
        padding: 0 4px; } }
.common-modal .modal-content .product-details .products {
    width: 100%;
    padding-left: 0.9375rem;
    padding-right: 0.9375rem; }
.common-modal .modal-content .product-details .products .product-list {
    padding: 0;
    margin: 0;
    list-style: none; }
.common-modal .modal-content .product-details .products .product-list li a {
    height: 40px;
    background-color: #f5f5f5;
    color: #544f40;
    padding: 0.5rem 0.9375rem;
    margin-bottom: 0.625rem;
    color: #544f40;
    display: block; }
.common-modal .modal-content .product-details .products .product-list li a:hover {
    color: #f36533; }
.common-modal .modal-content .product-details .products .product-list li a.active, .common-modal .modal-content .product-details .products .product-list li a:hover {
    background-color: #f36533;
    color: #FFF; }
.common-modal .modal-content .product-details .products .product-list li a.active a, .common-modal .modal-content .product-details .products .product-list li a:hover a {
    color: #FFF; }
.common-modal .modal-content .product-details .products .product-list li a.active a:hover, .common-modal .modal-content .product-details .products .product-list li a:hover a:hover {
    color: #FFF; }
.common-modal .modal-content .product-details .products .product-list.product-list-row {
    margin-right: -15px;
    margin-left: -15px; }
.common-modal .modal-content .product-details .products tr td {
    height: 40px;
    background-color: #f5f5f5;
    color: #544f40;
    padding: 0.5rem 0.9375rem;
    margin-bottom: 0.625rem;
    color: #544f40;
    display: block; }
.common-modal .modal-content .modal-footer {
    border: none;
    padding-top: 0;
    padding-bottom: 2.5rem;
    margin-bottom: 1rem; }
.common-modal .modal-content .modal-footer button {
    color: #FFF; }
.common-modal .modal-content .modal-footer span {
    font-family: "HelveticaLTStd-Bold", "Helvetica Neue", Helvetica, sans-serif;
    color: #f36533;
    font-size: 0.875rem;
    font-style: italic;
    padding-left: 0.3125rem;
    padding-right: 0.3125rem;
    position: relative;
    font-weight: 400;
    text-transform: uppercase;
    text-decoration: none; }
.common-modal .modal-content .modal-footer .btn-more-blue {
    color: #00617F;
    font-weight: 700;
    cursor: pointer;
    position: relative; }
.common-modal .modal-content .modal-footer .btn-more-blue a {
    color: #00617F; }
.common-modal .modal-content .modal-footer .btn-more-blue a:hover, .common-modal .modal-content .modal-footer .btn-more-blue a.active {
    color: #00617F;
    text-decoration: none; }
.common-modal .modal-content .modal-footer .btn-more-blue:hover, .common-modal .modal-content .modal-footer .btn-more-blue.active {
    color: #00617F;
    font-weight: 700;
    cursor: pointer;
    position: relative;
    text-decoration: none; }
.common-modal .modal-content .modal-footer .btn-more-blue:after {
    position: absolute;
    background: url(../img/two-line-gray.png) center center no-repeat;
    width: 1.125rem;
    height: 1.375rem;
    content: " ";
    display: inline-block;
    left: -7px;
    top: 50%;
    margin-top: -0.6875rem; }
.common-modal .modal-content .modal-footer .modal-footer-links {
    display: inline; }
@-moz-document url-prefix() {
    .common-modal .modal-content .modal-footer .modal-footer-links {
        display: contents; } }
@supports (-ms-ime-align: auto) {
    .common-modal .modal-content .modal-footer .modal-footer-links {
        display: flex; } }
@media screen and (min-width: 62em) {
    .common-modal .modal-content .modal-footer .model-padd {
        padding-left: 3.438rem;
        padding-right: 3.438rem; } }
.common-modal .modal-content .modal-footer .model-padd .inclusive-exclusive-popup .inclusive-exclusive-detail .inclusive-exclusive-holder {
    margin-bottom: 0.625rem; }
.common-modal .modal-content .modal-footer .model-padd .inclusive-exclusive-popup .inclusive-exclusive-detail .inclusive-exclusive-holder ul {
    list-style: disc;
    padding: 0;
    margin: 1rem 0 0; }
.common-modal .modal-content .modal-footer .model-padd .inclusive-exclusive-popup .inclusive-exclusive-detail .inclusive-exclusive-holder ul li {
    color: #544f40;
    position: relative;
    margin-bottom: 0.3125rem; }
.common-modal .modal-content .modal-footer .model-padd .inclusive-exclusive-popup .inclusive-exclusive-detail .inclusive-exclusive-holder ul li:first-child {
    list-style-type: none; }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .common-modal .modal-content .modal-footer {
        display: block; } }

.inclusive-exclusive-popup .inclusive-exclusive-detail .inclusive-exclusive-holder ul li:first-child {
    list-style-type: none; }

.thankyou .modal-content {
    border: 1px solid #f36533 !important; }
.thankyou .modal-content .thank-you .modaltitle {
    min-height: 54px; }
.thankyou .modal-content .thank-you .hd1 {
    border-bottom: 2px solid #f36533 !important;
    width: 169px;
    margin: 0 auto;
    padding: 0.3125rem 0; }
.thankyou .modal-content .thankyou-holder p {
    padding: 0;
    margin: 1.5rem 0 0; }

.fix-header .modal {
    margin-top: 5rem; }

.medical-condition-detail {
    margin: 10px 0; }
.medical-condition-detail .condition-holder {
    margin-bottom: 0.9375rem; }
.medical-condition-detail .condition-holder h6 a:hover, .medical-condition-detail .condition-holder h6 a.active {
    color: #FFF;
    background-color: #f36533; }

.dataTables_length {
    display: none; }

.dataTables_filter {
    display: -ms-flexbox;
    display: flex;
    -ms-flex-wrap: wrap;
    flex-wrap: wrap;
    margin-bottom: 1.25rem; }
.dataTables_filter > .key-search {
    position: relative;
    width: 100%;
    min-height: 1px;
    padding-left: 0;
    -ms-flex: 0 0 100%;
    flex: 0 0 100%;
    max-width: 100%;
    padding-right: 0; }
@media screen and (min-width: 62em) {
    .dataTables_filter > .key-search {
        position: relative;
        width: 100%;
        min-height: 1px;
        padding-left: 0;
        -ms-flex: 0 0 58.333333%;
        flex: 0 0 58.333333%;
        max-width: 58.333333%;
        padding-right: 0.9375rem; } }
.dataTables_filter > .key-search > span {
    display: block;
    font-weight: 700;
    color: #544f40;
    margin-bottom: 0.1875rem; }
.dataTables_filter > .key-search > label {
    width: 100%; }
.dataTables_filter > .pub-year {
    position: relative;
    width: 100%;
    min-height: 1px;
    padding-right: 0;
    -ms-flex: 0 0 100%;
    flex: 0 0 100%;
    max-width: 100%;
    padding-left: 0; }
@media screen and (min-width: 62em) {
    .dataTables_filter > .pub-year {
        position: relative;
        width: 100%;
        min-height: 1px;
        padding-right: 0;
        -ms-flex: 0 0 41.666667%;
        flex: 0 0 41.666667%;
        max-width: 41.666667%;
        padding-left: 0.9375rem; } }
.dataTables_filter > .pub-year > span {
    display: block;
    font-weight: 700;
    color: #544f40;
    margin-bottom: 0.1875rem; }

.dataTables_wrapper div.row:first-child div[class*="col-md"] {
    -ms-flex: 0 0 100%;
    flex: 0 0 100%;
    max-width: 100%; }
.dataTables_wrapper .pagination {
    -ms-flex-pack: center !important;
    justify-content: center !important; }
@media screen and (min-width: 36em) {
    .dataTables_wrapper .pagination {
        -ms-flex-pack: end !important;
        justify-content: flex-end !important; } }
.dataTables_wrapper .pagination .page-item .page-link {
    color: #544f40;
    outline: none;
    box-shadow: none;
    border-width: 1px; }
.dataTables_wrapper .pagination .page-item .page-link span[aria-hidden="true"] {
    display: block;
    width: 0.875rem;
    height: 1.25rem;
    background: url(../img/pagination-arrow.png) no-repeat center center; }
.dataTables_wrapper .pagination .page-item .page-link span[aria-hidden="true"]:hover, .dataTables_wrapper .pagination .page-item .page-link span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }
.dataTables_wrapper .pagination .page-item .page-link:hover {
    color: #FFF;
    text-decoration: none;
    background-color: #f36533;
    border-color: #f36533; }
.dataTables_wrapper .pagination .page-item .page-link:hover span[aria-hidden="true"] {
    background-image: url(../img/pagination-arrow-hover.png); }
.dataTables_wrapper .pagination .page-item .page-link:hover span[aria-hidden="true"]:hover, .dataTables_wrapper .pagination .page-item .page-link:hover span[aria-hidden="true"].active {
    background-image: url(../img/pagination-arrow-hover.png); }
.dataTables_wrapper .pagination .page-item .page-link:focus {
    outline: none;
    box-shadow: none;
    border: 1px solid #dee2e6; }
.dataTables_wrapper .pagination .page-item.active .page-link {
    background-color: #f36533;
    border-color: #f36533;
    color: #FFF; }
.dataTables_wrapper .pagination .page-item.previous .page-link i {
    background: url(../img/pagination-arrow-l.png) center center no-repeat;
    display: block;
    width: 0.875rem;
    height: 1.25rem; }
.dataTables_wrapper .pagination .page-item.previous:hover .page-link i {
    background: url(../img/pagination-arrow-hover-l.png) center center no-repeat; }
.dataTables_wrapper .pagination .page-item.previous.disabled .page-link i {
    background: url(../img/pagination-arrow-l.png) center center no-repeat;
    display: block;
    width: 0.875rem;
    height: 1.25rem; }
.dataTables_wrapper .pagination .page-item.previous.disabled:hover .page-link i {
    background: url(../img/pagination-arrow-l.png) center center no-repeat; }
.dataTables_wrapper .pagination .page-item.next .page-link i {
    background: url(../img/pagination-arrow.png) center center no-repeat;
    display: block;
    width: 0.875rem;
    height: 1.25rem; }
.dataTables_wrapper .pagination .page-item.next:hover .page-link i {
    background: url(../img/pagination-arrow-hover.png) center center no-repeat; }
.dataTables_wrapper .pagination .page-item.next.disabled .page-link i {
    background: url(../img/pagination-arrow.png) center center no-repeat;
    display: block;
    width: 0.875rem;
    height: 1.25rem; }
.dataTables_wrapper .pagination .page-item.next.disabled:hover .page-link i {
    background: url(../img/pagination-arrow.png) center center no-repeat; }

.dataTables_info {
    color: #544f40;
    margin-top: 0.4375rem;
    margin-bottom: 0.9375rem;
    text-align: center; }
@media screen and (min-width: 36em) {
    .dataTables_info {
        text-align: left; } }

.dataTable tfoot {
    display: none; }

@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .common-modal .modal-content .modal-footer,
    .medical-condition .modal-content .modal-footer {
        display: block; } }
@media all and (-ms-high-contrast: none), (-ms-high-contrast: active) {
    .common-modal .modal-content .modal-footer .modal-footer-links,
    .medical-condition .modal-content .modal-footer .modal-footer-links {
        float: right; } }

.sitemap-section {
    margin: 1.875rem 0 3rem 0; }
.sitemap-section .sitemap-links-section {
    width: 100%;
    display: block;
    font-size: 1.125rem; }
.sitemap-section .sitemap-links-section h1 {
    font-size: 1.625rem;
    font-weight: 400;
    color: #f36533; }
.sitemap-section .sitemap-links-section .sitemap {
    padding: 0; }
.sitemap-section .sitemap-links-section .sitemap ul {
    list-style: none; }
.sitemap-section .sitemap-links-section .sitemap ul:before {
    list-style-type: none; }
.sitemap-section .sitemap-links-section .sitemap ul li {
    font-size: 1.25rem;
    margin: 0 0 0 0.625rem;
    position: relative;
    line-height: 2.5rem; }
.sitemap-section .sitemap-links-section .sitemap ul li:before {
    background-color: #f36533;
    border: 1px solid transparent;
    border-radius: 50%;
    content: '';
    height: .3em;
    left: 0;
    min-height: 0.3125rem;
    min-width: 0.3125rem;
    position: absolute;
    top: .5em;
    width: .3em; }
.sitemap-section .sitemap-links-section .sitemap ul li a {
    transition: color 0.3s ease;
    color: #15717d;
    text-decoration: none;
    background: transparent; }
.sitemap-section .sitemap-links-section .sitemap ul li ul {
    list-style: none; }
.sitemap-section .sitemap-links-section .sitemap ul li ul li {
    font-size: 1.125rem;
    position: relative;
    margin: 0 0 0 0.625rem;
    line-height: 2.5rem; }
.sitemap-section .sitemap-links-section .sitemap ul li ul li::before {
    border: 1px solid transparent;
    border-radius: 50%;
    content: '';
    height: .3em;
    left: 0.625rem;
    min-height: 0.3125rem;
    min-width: 0.3125rem;
    position: absolute;
    top: .9em;
    width: .3em;
    background: #ffffff;
    border-color: #f36533; }
.sitemap-section .sitemap-links-section .sitemap ul li ul li .expanded,
.sitemap-section .sitemap-links-section .sitemap ul li ul li .collapsed,
.sitemap-section .sitemap-links-section .sitemap ul li ul li .leaf {
    padding: 1.2em 0.5em 0 0;
    margin: 0; }
@media screen and (min-width: 48em) {
    .sitemap-section .sitemap-links-section .sitemap ul li ul li {
        padding: 0 1rem; } }
@media screen and (min-width: 48em) {
    .sitemap-section .sitemap-links-section .sitemap ul li {
        padding: 0 1rem; } }
.sitemap-section .sitemap-links-section .sitemap ul li .expanded,
.sitemap-section .sitemap-links-section .sitemap ul li .collapsed,
.sitemap-section .sitemap-links-section .sitemap ul li .leaf {
    padding: 1.2em 0.5em 0 0;
    margin: 0; }

@media screen and (min-width: 75em) {
    #gsk-footer-contact-form .contact-section .contact-form-section {
        margin: 2.75rem 0; } }
@media screen and (max-width: 62em) {
    #gsk-footer-contact-form .contact-section .contact-form-section {
        margin: 1.875rem 0; } }
#gsk-footer-contact-form .contact-section .contact-form-section form {
    padding: 0;
    margin: 0; }
#gsk-footer-contact-form .contact-section .contact-form-section form p {
    color: #544f40;
    font-weight: 400; }
#gsk-footer-contact-form .contact-section .contact-form-section form .select-country .selectric-form-control .selectric {
    padding: .375rem .75rem; }
#gsk-footer-contact-form .contact-section .contact-form-section form .select-country .selectric-form-control .selectric .label {
    margin: 0;
    line-height: 2.5; }
#gsk-footer-contact-form .contact-section .contact-form-section form .select-country .selectric-form-control .selectric .button {
    height: 100%; }
#gsk-footer-contact-form .contact-section .contact-form-section form .for-item-country .selectric-custom-select-xl {
    padding: .5rem 1rem;
    line-height: 1.5; }
#gsk-footer-contact-form .contact-section .contact-form-section form .form-item-message .resizable-textarea .grippie {
    background: #eee url(../img/grippie.png) no-repeat center 2px;
    border: 1px solid #ddd;
    border-top-width: 0;
    cursor: s-resize;
    height: 9px;
    overflow: hidden; }

#gsk-footer-contact-form select {
    font-size: 0.875rem; }

.glossary-section .glossary-data-section h1 {
    margin-bottom: 1.25rem; }
.glossary-section .glossary-data-section .glossary-tabs {
    margin: 1.125rem 0 0.625rem 0; }
.glossary-section .glossary-data-section .glossary-tabs ul {
    margin: 1.563rem 0 0.625rem 0;
    position: relative;
    padding: 0;
    width: 100%;
    margin: 0; }
.glossary-section .glossary-data-section .glossary-tabs ul li {
    display: inline-block;
    float: left;
    border: 0;
    margin-bottom: 0.625rem;
    margin-right: 1%;
    width: 24%;
    height: 2.188rem;
    padding: 0;
    text-transform: uppercase;
    background-color: #f36533;
    color: #FFF;
    font-weight: bolder;
    font-size: 0.75rem;
    letter-spacing: 0.0625rem; }
.glossary-section .glossary-data-section .glossary-tabs ul li a {
    margin: 0;
    line-height: 2.188rem;
    text-align: center;
    display: block;
    color: #fff;
    text-decoration: none;
    font-size: 1rem; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl {
    color: #544f40; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl dt {
    font-size: 1rem;
    font-weight: 700; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl dd {
    margin-bottom: .5rem;
    margin-left: 0;
    border-bottom: 0.0625rem solid #d5d1ce;
    width: 100%;
    padding: 0.625rem 0; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl dd:last-child {
    border-bottom: none; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl dd ol {
    padding: 0;
    margin: 0.375rem 1rem; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container dl dd ul {
    list-style-type: none;
    padding: 0;
    margin: 0.375rem 0; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container #tab_1_contents {
    display: block; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container #tab_2_contents {
    display: none; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container #tab_3_contents {
    display: none; }
.glossary-section .glossary-data-section .glossary-list .tab_contents_container #tab_4_contents {
    display: none; }

table.dataTable thead th {
    position: relative;
    background-image: none !important; }
table.dataTable thead th.sorting:after {
    position: absolute;
    top: 6px;
    right: 8px;
    display: block;
    font-family: FontAwesome;
    font-size: 14px;
    color: #ffffff;
    padding: 0;
    content: "\f0dc";
    font-size: 14px;
    color: #ffffff;
    padding: 0; }
@media screen and (max-width: 48em) {
    table.dataTable thead th.sorting:after {
        margin-top: 0.875rem; } }
table.dataTable thead th.sorting_asc:after {
    position: absolute;
    top: 6px;
    right: 8px;
    display: block;
    font-family: FontAwesome;
    font-size: 14px;
    color: #ffffff;
    padding: 0;
    content: "\f062"; }
@media screen and (max-width: 48em) {
    table.dataTable thead th.sorting_asc:after {
        margin-top: 0.875rem; } }
table.dataTable thead th.sorting_desc:after {
    position: absolute;
    top: 6px;
    right: 8px;
    display: block;
    font-family: FontAwesome;
    font-size: 14px;
    color: #ffffff;
    padding: 0;
    content: "\f063"; }
@media screen and (max-width: 48em) {
    table.dataTable thead th.sorting_desc:after {
        margin-top: 0.875rem; } }

#gsk-footer-contact-form .form-group  p{
    margin: 1.8rem 0;
}
.gsk-pdf-icon {
    position:relative;
}
.gsk-pdf-icon::after{
    width: 2.5rem;
    height: 100%;
    background: url(../img/icon-pdf@2x.png) #f36533 no-repeat center center;
    background-size: 26px 26px;
    right: 0;
    top: 0;
    border-left: solid 1px #f36533;
    position: absolute;
    content: " ";
}
/*# sourceMappingURL=styles.css.map */